Antimicrobial Resistance Clinical Trial
Official title:
Surveillance of Healthcare-associated Infections & Antimicrobial Resistance
NCT number | NCT05734391 |
Other study ID # | 851492 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | October 1, 2022 |
Est. completion date | December 20, 2023 |
Verified date | March 2024 |
Source | University of Pennsylvania |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The aims of this project, called "Surveillance of Healthcare-associated infections & Antimicrobial Resistance", or "SHARE", are to 1) enhance laboratory capacity to detect emerging AMR patterns; 2) strengthen hospital epidemiology programs to use data to prevent, detect, and contain emerging AMR threats; 3) deploy study teams to answer critical public health surveillance questions, and 4) to build a national network of infection prevention and control (IPC) resources to prevent, detect, and contain emerging infectious disease threats
Status | Completed |
Enrollment | 1500 |
Est. completion date | December 20, 2023 |
Est. primary completion date | December 20, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - hospital inpatient admission to participating wards. Exclusion Criteria: - diagnosis of a bleeding disorder - platelet counts of <50,000 - diagnosis of coagulopathy - presence of active bleeding - inability to have a nares swab collected due to some other condition where nasal swabbing would be contraindicated - inability to have a rectal swab collected due to some other condition where rectal swabbing would be contraindicated |
Country | Name | City | State |
---|---|---|---|
Botswana | Princess Marina Hospital | Gaborone | |
United States | University of Pennsylvania School of Medicine | Philadelphia | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
University of Pennsylvania |
United States, Botswana,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Expertise | Ultimately, the goal of the SHARE project is to assemble the expertise and infrastructure needed to build a resilient HAI/AMR surveillance system fully-incorporated into MOHW's surveillance activities. The project aims to build capacity, both material and knowledge, in existing laboratory and IPC teams to face the dynamic challenges posed by HAIs and AMR | 12 months | |
Secondary | Feasibility and Surveillance | SHARE's "Colonization Feasibility Study", will seek to assess the feasibility and surveillance potential of routine MDRO screening in hospitals, determining whether MDRO colonization can provide an "early warning system" for emerging AMR threats | 12 months |
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