Clinical Trials Logo

Clinical Trial Summary

Coronary endarterectomy (CE) combined with coronary artery bypass grafting (CABG) can be the final option for achieving complete revascularization in diffuse coronary artery disease patients. Since the exposure of subendothelial tissue to the blood flow after CE, the coagulation cascade can be activated, resulting in the increased risk of graft failure. Therefore, anticoagulation with warfarin in this group of patients might be beneficial. However, evidence is limited. This study aims to compare the clinical outcomes between dual antiplatelet therapy with or without warfarin after CE+CABG.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05782270
Study type Interventional
Source China National Center for Cardiovascular Diseases
Contact Xieraili Tiemuerniyazi, M.D.
Phone 010-88322265
Email tiemuernyz@mail2.sysu.edu.cn
Status Recruiting
Phase Phase 4
Start date April 11, 2023
Completion date June 30, 2025

See also
  Status Clinical Trial Phase
Completed NCT02705976 - Prospective Trial of a Validated Algorithm for Warfarin Dosing N/A
Active, not recruiting NCT04139525 - Comparison of Citrate and Heparin Anticoagulation During Hemodialysis With MCO PES-PVP (Theranova) Membrane N/A
Completed NCT01907048 - Patient and Physician Knowledge of Key Safety Messages
Recruiting NCT03419923 - Three Anticoagulation Strategies for Hemodialysis in Patients at Risk of Hemorrhage N/A
Completed NCT03575936 - Enhanced Pharmacist-Managed Anticoagulation Service in a University-based Family Medicine Clinic N/A
Completed NCT02714855 - Apixaban in the Prevention of Stroke and Systemic Embolism in Patients With Atrial Fibrillation in Real-Life Setting in France N/A
Recruiting NCT01314235 - Influence of Clonidine on Thrombozytes of Blood of Patients Under Anticoagulation Therapy With ASS and Clopidogrel N/A
Withdrawn NCT04059965 - AntiCoagulation Tracking InterVention and Evaluation N/A
Recruiting NCT02987192 - Minimally Invasive Lumbar Aneasthesia Used for Cesarean Section N/A
Completed NCT01477528 - Study of Reduced Anti-coagulation/Anti-platelet Therapy in Patients With the HeartMate II Left Ventricular Assist System (LVAS) (TRACE)
Recruiting NCT04405232 - Coagulopathy in COVID19 - A Multi-Centre Observational Study in UK
Recruiting NCT02761941 - Excessive Warfarin Anticoagulation - Causes and Consequences N/A
Completed NCT02392104 - Prospective Evaluation of an Extended Interval of INR Follow-up in a VA Anticoagulation Service N/A
Completed NCT01884337 - Multi-center Study to Evaluate the Safety of Apixaban (BMS-562247) in Indian Subjects Undergoing Elective Total Knee Replacement or Total Hip Replacement Surgery Phase 4
Recruiting NCT03473132 - Assessment of Coagulation Factor Levels in Left Ventricular Device (LVAD )Patients Following Temporary Warfarin Reversal With Four Factor Prothrombin Complex Concentrate (4F-PCC) Phase 4
Enrolling by invitation NCT05305612 - Optimal PeriproCeduraL AnticOagulation in Structural Transseptal Interventions Phase 4
Completed NCT03662594 - Growth of High-Quality Oxides on The Inner Surface of ECMO Circuit by ALD to Reduce Thrombus Formation N/A
Active, not recruiting NCT03910933 - Electronic KIDCLOT Interactive Thrombosis/Thrombophilia Education; A Quality Assurance Initiative
Completed NCT02492828 - Adherence of Apixaban and Warfarin in Patients With Arterial Fibrillation in Real-world Setting in Sweden N/A
Completed NCT03684395 - Accessibility to New Drugs Versus SOC in Sweden