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DSA Risk Factors in MMF-based Immunosuppressed Post-transplanted Patients — DRFMBIPTP  

Antibody-mediated Rejection Clinical Trial

Official title:
DSA Risk Factors in Chinese Kidney Transplant Patients Using MPA-based Immunosuppression Protocol: A Multi-center Clinical Study

Clinical Trial Summary

Kidney transplantation is the best therapy method for patients with uremia. The main factors affecting the long-term survival of the graft were chronic antibody-mediated rejection and the death of the patients. Newborn donor special antibody (DSA) is a major risk factor for chronic antibody-mediated rejection (AMR) and poor transplantation outcomes. Detection of mycophenolate mofetil (MMF) trough concentration can help estimate its exposure. Deficient exposure of MMF can lead to AMR after transplantation surgery. The aim of this study is to estimate the risk factors of one-year DSA after transplantation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04368962
Study type Observational
Source First Affiliated Hospital Xi'an Jiaotong University
Contact Wujun Xue, Prof.
Phone +86 13991990128
Email xwujun163@mail.xjtu.edu.cn
Status Recruiting
Phase
Start date January 22, 2021
Completion date December 1, 2023
View Details
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