Antibiotic Dosing in Patients on Intermittent Hemodialysis

Status Completed

Clinical Trial Summary

The adequacy of the currently used dosing regimen of glycopeptides (vancomycin and teicoplanin) and beta-lactam antibiotics (amoxicillin-clavulanic acid, piperacillin-tazobactam, ceftazidim) in patients with end-stage kidney disease receiving intermittent hemodialysis is studied by evaluating pharmacokinetics-pharmacodynamics (PK-PD) target attainment. A population pharmacokinetic study is performed to assist the selection of the optimal individualized dose for patients undergoing intermittent dialysis, taking into consideration as many relevant variables as possible.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03909698
Study type	Observational
Source	University Hospital, Ghent
Contact
Status	Completed
Phase
Start date	September 15, 2016
Completion date	March 31, 2022

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04892745` - Impact of Hemodialysis on Cutaneo-muscular Electrical Impedance
Not yet recruiting	`NCT04925674` - Study of HEC53856 in Patients With Subjects With End-Stage Renal Disease Receiving Dialysis.	Phase 1
Active, not recruiting	`NCT03183245` - Comparison of the Human Acellular Vessel (HAV) With Fistulas as Conduits for Hemodialysis	Phase 3
Completed	`NCT03365635` - Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C	Phase 4
Withdrawn	`NCT02904343` - Evaluation of Domestic Hemodialysis Machine: A Multi-center Clinical Study	N/A
Withdrawn	`NCT01855334` - L-Arginine and Spironolactone Trial in Dialysis-Dependent ESRD	Phase 4
Completed	`NCT01700465` - Estimating and Predicting Hemodynamic Changes During Hemodialysis	N/A
Recruiting	`NCT01195519` - The Assessment of Quality of Life in Patients With Peritoneal Dialysis and Hemodialysis	N/A
Completed	`NCT00737672` - GORE VIABAHN Endoprosthesis Versus Percutaneous Transluminal Angioplasty (PTA) to Revise AV Grafts in Hemodialysis	Phase 3
Completed	`NCT00527774` - Effect of HCV Infection on Insulin Resistance and Malnutrition-inflammation Complex Syndrome in Regular Hemodialysis Patients	N/A
Completed	`NCT00942253` - Exercise Training in Dialysis Patients With Restless Legs Syndrome (RLS)	Phase 2
Completed	`NCT00224081` - DRIVE Trial (Dialysis Patients' Response to Intravenous [IV] Iron With Elevated Ferritin)	Phase 4
Completed	`NCT00850252` - Use of a Lifeline Graft in the A-V Shunt Model	Phase 1/Phase 2
Completed	`NCT00776750` - Influenza Vaccination in Hemodialysis Patients and Renal Transplant Recipients	Phase 4
Recruiting	`NCT06351007` - Educational Program on Dietary Adherence and Nutritional Knowledge in Chronic Kidney Disease Patients (EPAK)	N/A
Withdrawn	`NCT03664141` - Impact of Cannabis Oil on Nutrition in Hemodialysis Patients Study (ICON-HP Study)	Phase 3
Recruiting	`NCT03311321` - Vitamin K to Slow Progression of Cardiovascular Disease Risk in Hemodialysis Patients	N/A
Recruiting	`NCT06098924` - HD Patients' Depression and Happiness
Recruiting	`NCT03419923` - Three Anticoagulation Strategies for Hemodialysis in Patients at Risk of Hemorrhage	N/A
Completed	`NCT03470727` - The Effect of Citrate Dialysate on Clot Formation and Anemia in Hemodialysis Patients	N/A