Merck IISP Stewardship Grant for Antibiotic Best Practices

Antibiotic Resistant Infection Clinical Trial

Official title:

Implementation of Antimicrobial Stewardship and Decision Support Into the EPIC Electronic Medical Record

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01573195
• Other study ID #: 2012-0168 (MSN141105)
• Secondary ID: Merk Dr Fox
• Status: Completed
• Phase: Phase 4
• First received: May 4, 2011
• Last updated: December 16, 2014
• Start date: March 2011
• Est. completion date: April 2012

Study information

• Verified date: December 2014
• Source: University of Wisconsin, Madison
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to pilot the use of best practices alerts to enhance an antimicrobial stewardship program using the electronic medical record, EPIC.

Description:

The purpose of this study is to pilot the use of best practices to enhance an antimicrobial stewardship program using the electronic medical record, EPIC. Screening information technology tools via SETNET/Safety SUrveyor(Premier) and the electronic anti-infective order form would allow for sufficient medical record review to create best practices alerts for the purpose of appropriate de-escalation of anti-invectives.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1285
• Est. completion date: April 2012
• Est. primary completion date: April 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Physicians with prescribing privileges at the UWHC

Exclusion Criteria:

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

• Antibiotic Resistant Infection

Locations

Country	Name	City	State
United States	University of Wisconsin Hospitals and Clinics	Madison	Wisconsin

Sponsors (1)

Lead Sponsor	Collaborator
University of Wisconsin, Madison

Country where clinical trial is conducted

United States, 

References & Publications (1)

Schulz L, Osterby K, Fox B. The use of best practice alerts with the development of an antimicrobial stewardship navigator to promote antibiotic de-escalation in the electronic medical record. Infect Control Hosp Epidemiol. 2013 Dec;34(12):1259-65. doi: 1 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percentage of best practice alerts(BPA) that were completely accepted, partially accepted, or rejected within 72 hours of issuing the BPA	after issuing the BPA for deescalation, the responding healthcare provider will respond in one of the manners above	One Year	No
Secondary	The number and type of antiinfectives that were administered before and after(11days) the best practice alert is issued.	The antiinfective use before and after the BPA will be analyzed in detail. The number of antibiotics, percentage decrease(or less likely increase) in antiinfectives in the 3 days before BPA , and 11 days after the BPA will be analyzed. A cost analysis will be performed. Patient outcomes will not be assessed.	One year	No

External Links

•   ICHE publication