Management and Outcome of Fever in Children in Europe

Antibiotic Prescription Clinical Trial

— MOFICHE  

Official title:

Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05221437
• Other study ID #: REC ref: 16/LO/1684-S
• Status: Completed
• Start date: January 1, 2017
• Est. completion date: December 31, 2021

Study information

• Verified date: January 2022
• Source: Imperial College London
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This is an observational study assessing the management and outcome of children presenting to Emergency Departments (ED) with fever across Europe.

Description:

This is an observational study assessing the management and outcome of children presenting to Emergency Departments (ED) with fever across Europe. This study will use large departmental datasets to collect information on at least 50,000 febrile episodes . This study will use large-scale, pseudo-anonymized departmental data, and will not involve consented patient recruitment; nor will it use patient samples. Data included in MOFICHE will be based on that collected as part of routine clinical care. Antibiotic prescription, hospitalisation and number/type of investigations, re-attendance at ED within 5 days of the first hospital presentation will be recorded.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 38480
• Est. completion date: December 31, 2021
• Est. primary completion date: April 1, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 18 Years

Eligibility

Inclusion Criteria:

• aged 0- 18 years visiting the emergency care.

• fever measured at ED or history of (measured) fever less than 3 consecutive days prior to presentation at emergency department

Exclusion Criteria:

-

Related Conditions & MeSH terms

• Antibiotic Prescription

Intervention

Other:
• antibiotic prescription

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Imperial College London

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Antibiotic prescription	number of antibiotic prescriptions	one year
Primary	hospitalization	number of children requiring admission to hospital	one year
Primary	Number of investigations	number of investigations	one year
Primary	Number of children re-attending within 5 days of the first hospital presentation.	Number of re-attendance	one year