Anti-Mullerian Hormone Clinical Trial
Official title:
Anti-Mullerian Hormone Levels Variations Following an Open Myomectomy
NCT number | NCT01723085 |
Other study ID # | AMH |
Secondary ID | |
Status | Terminated |
Phase | |
First received | |
Last updated | |
Start date | March 2012 |
Est. completion date | December 2015 |
Verified date | July 2018 |
Source | OVO R & D |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. It is well known that ovarian
surgery for endometriosis lowers Anti-Mullerian hormone, but little is known for other
surgeries. We seek to investigate the hormone variations before and after an open myomectomy.
Hypothesis: Anti-Mullerian hormone levels drop following surgery but return to normal levels
in a few months
Status | Terminated |
Enrollment | 21 |
Est. completion date | December 2015 |
Est. primary completion date | December 2015 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 42 Years |
Eligibility |
Inclusion Criteria: - 18 to 42 years old - Requiring open myomectomy for any indication Exclusion Criteria: - Incapable of informed consent - Use of hormonal contraception or Gonadotropin-releasing hormone agonists in the past 3 months - Woman over 42 years old - Post-menopause women - Positive B-human chorionic gonadotropin the day of surgery - Ovarian surgery (at the same time) - Pre-operative AMH below 0.3 ng/mL |
Country | Name | City | State |
---|---|---|---|
Canada | Hopital Saint-Luc | Montreal | Quebec |
Lead Sponsor | Collaborator |
---|---|
OVO R & D |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Anti-Mullerian Hormone levels variation | Anti-Mullerian Hormone levels before and 6 months after surgery | 6 months |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03131388 -
Clinical Performance Evaluation of AMH Assay
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||
Active, not recruiting |
NCT00928044 -
The Impact of Gynecological Surgery on Ovarian Function in Women of Reproductive Age: Postoperative Changes of Serum Anti-Müllerian Hormone (AMH)
|
N/A |