Clinical Trials Logo

Clinical Trial Summary

This study primarily aims to investigate arthrogenic muscle inhibition (AMI), an underlying mechanism in patellofemoral pain (PFP), which remain to date understudied. Although, studies have revealed that AMI needs to be eliminated before improvements in muscle strength can be achieved, to date quadriceps muscle inhibition in patients with PFP remains understudied. To date the influence of AMI on functional performance and the direct link to pain in patients with PFP remain unclear. This study aims to investigate the link between AMI to pain, functional performance and how an acute treatment can affect functional performance and pain.


Clinical Trial Description

Patellofemoral pain (PFP) is one of the most frequently diagnosed conditions in patients with knee complaints.

Studies investigating the therapeutic effect on PFP revealed that the majority of patients with PFP were still suffering of knee pain after 5 to 8 years, despite initially received treatment and education, indicating that the current treatments fail to prevent the chronicity of symptoms. Considering that current treatment-strategies of patients with PFP seem to be unable to avoid the development of chronic symptoms, the question arises if the underlying factors of PFP are understood sufficiently.

In contrary to the current broad body of literature on weakness, potentially underlying factors which might influence or even lead to PFP, such arthrogenic muscle inhibition (AMI) or the break phenomenon remain understudied.

Pain in PFP has been proven to be linked to quadriceps strength deficit, gluteal strength deficits, knee stability, irregularities in the quadriceps torque curve, and functional performance. Bazett et al. (2011) described that pain "is more than a symptom and might play a role in the etiology or progression of PFP". Furthermore, pain seems to play a crucial role in AMI. However, the correlation between pain and AMI in patients with PFP has not been investigated currently.

No assessment in isolation can provide a full picture of the problem. The combination of AMI, the break phenomenon with a biomechanical analysis might enable the determination of the impact of inhibition and strength on biomechanical changes. In addition, it might provide an answer to whether AMI or weakness cause biomechanical alterations, which would help to optimise treatment approaches in PFP.

The PowersTM strap strap was developed with the aim of assisting lower limb kinematics, decreasing knee varus through supporting femoral abduction and external rotation. This treatment may potentially also directly improve functional performance. As the functional performance in participants with PFP after the application of the PowersTM strap has not been investigated, this study aims to analyse if there is a direct link between the application of the PowersTM strap to functional performance and pain. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02914574
Study type Interventional
Source University of Salford
Contact
Status Completed
Phase N/A
Start date June 2016
Completion date October 2017

See also
  Status Clinical Trial Phase
Recruiting NCT06197958 - Comparison of Concentric-eccentric Exercises in Patellofemoral Pain Syndrome N/A
Not yet recruiting NCT05497661 - Ultrasound Patellar Tendon Assessment N/A
Recruiting NCT05403944 - Strength or Power Training for Patellofemoral Pain N/A
Not yet recruiting NCT05576064 - Is Gait Analysis for Proposed Rotational Deformities a Useful Resource
Completed NCT04099004 - Neural Correlates of Knee Sensorimotor Control in Patients With Patellofemoral Pain Syndrome N/A
Completed NCT03743519 - The Efficacy of a Tart Cherry Drink for the Treatment of Patellofemoral Pain in Recreational Athletes. N/A
Completed NCT00662493 - A Comparison of Two Exercise Programs on Knee Motor Control Phase 2
Recruiting NCT05285007 - Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain N/A
Recruiting NCT05501210 - Vibration on Patellofemoral Joint Pain After ACLR N/A
Recruiting NCT02786784 - The Role of Arthrogenic Muscular Inhibition in Patellofemoral Pain and the Response to an Exercise Programme N/A
Completed NCT05471089 - Long-term Effects of the Addition of Diathermy by Emission of Radiofrequency to Therapeutic Exercise in Patellofemoral Pain Syndrome Patients N/A
Active, not recruiting NCT05976269 - Bilateral Knee Pain and Dry Needling N/A
Completed NCT02025400 - Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial Phase 1
Recruiting NCT05811637 - Investigation of the Effect of Pilates Exercises on Patellofemoral Pain N/A
Completed NCT03392688 - Time Difference Between Onsets of Lateral And Medial Hamstring Muscles During Gait in Patients With Patellofemoral Pain. N/A
Completed NCT05995210 - Comparing the Effectiveness of Kinesio Taping and Knee Orthosis in Patients With Patellofemoral Pain Syndrome N/A