Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.


Clinical Trial Description

Patients undergoing arthroscopic knee surgery (ACL and non-ACL surgery) typically receive an ultrasound-guided femoral nerve block or an adductor canal block in the pre-operative phase for post-operative pain control. While an effective method for post-operative analgesia, the femoral nerve block is associated with profound quadriceps weakness for the duration of the nerve block, which can impair ambulation, rehabilitation, and increase the risk of falls. The more distal adductor canal block, however, contains primarily sensory branches of the femoral nerve and has been been purported by small volunteer studies to provide equally effective analgesia with minimal motor block and quadriceps weakness (as compared to femoral nerve block). The investigators will prospectively randomize patients undergoing knee arthroscopy at the UCSF Orthopaedic Institute to receive either a single-shot femoral nerve or adductor canal block pre-operatively after taking baseline measurements of quadriceps strength (quantified by maximum voluntary isometric contraction). The quadriceps muscle strength will be checked 20 minutes after the nerve block to assess strength. All patients will subsequently undergo a general anesthetic. The primary outcome variable will be post-block quadriceps strength as a percentage of baseline from pre-block values. Secondary outcome variables that will also investigated include: VAS pain score in the post anesthesia recovery unit and post-operative day 1, time to onset of sensory block, duration of nerve blockade, block performance time, patient satisfaction score, perioperative opioid use, perioperative analgesic consumption, incidence of paresthesias, number of needle passes, incidence of post-operative nausea, vomiting, constipation, and any other complications. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05190120
Study type Interventional
Source University of California, San Francisco
Contact
Status Completed
Phase Phase 4
Start date January 2016
Completion date March 20, 2022

See also
  Status Clinical Trial Phase
Completed NCT05109871 - Reliability and Validity of Inline Dynamometry Study for Measuring Knee Extensor Torque N/A
Recruiting NCT04088227 - Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears Phase 2
Completed NCT04956393 - The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study N/A
Recruiting NCT05574946 - Comparison of Two ACL Reconstruction Techniques: All-inside Versus Complete Tibial Tunnel Technique N/A
Completed NCT01447277 - Prospective Femoral Versus Femoral and Sciatic Nerve Block for Anterior Cruciate Ligament (ACL) Reconstruction N/A
Terminated NCT02911909 - Moderated Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction N/A
Completed NCT02760589 - Magnetic Resonance Imaging and Functional Performance Outcome After ACL Repair With Internal Brace Technique
Completed NCT02787096 - Dynamic Knee Laxity Measurement Coupled to MRI in Cases of Suspected Partial Anterior Cruciate Ligament Tear N/A
Completed NCT04635579 - Personalized Blood Flow Restriction for Anterior Cruciate Ligament Rehabilitation N/A
Completed NCT01850758 - Regenexx™ SD Versus Exercise Therapy for ACL Tears N/A
Recruiting NCT05204836 - Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee Injury Phase 1
Recruiting NCT04592471 - Assessment of the Safety and Performance of Knee Ligament Supports in the Context of a Return to Sport After Sprain
Completed NCT01580722 - Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing Phase 2
Recruiting NCT05174611 - Vitamin D to Improve Quadricep Muscle Strength Phase 2
Recruiting NCT05501210 - Vibration on Patellofemoral Joint Pain After ACLR N/A
Recruiting NCT05682820 - Analysis of Radiological Features of Lateral Femoral Impaction Fracture / Lateral Femoral Notch Sign
Terminated NCT02930122 - IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions Phase 2
Recruiting NCT05306054 - Physical Activity, Knee Joint Loading and Joint Health
Completed NCT04374968 - Use of Blood Flow Restriction Therapy Following ACL Tear N/A
Recruiting NCT04998656 - Werewolf Flow 50 During ACL Reconstruction N/A