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Clinical Trial Summary

The aim of this study was to determine the status of ovarian reserve in patients with ankylosing spondylitis (AS) using anti-mullerian hormone (AMH) level and antral follicle count (AFC). Women with AS and women controls diagnosed according to the classification criteria proposed by the American-European Consensus Group will be included in the study. Ovarian reserve will be evaluated in terms of clinical findings, AFC and serum AMH and reproductive hormone levels.

Researchers predict that the ovarian reserve may be reduced in patients with AS due to the autoimmune process and the pathophysiology of the disease. Serum AMH and ovarian AFC may be useful for assessing ovarian reserve. It is aimed to determine the course of ovarian reserve abnormalities and the best possible biomarkers of reduced ovarian reserve in patients with AS.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04209881
Study type Observational
Source Kanuni Sultan Suleyman Training and Research Hospital
Contact
Status Completed
Phase
Start date December 19, 2019
Completion date May 19, 2020

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