Ankylosing Spondylitis Clinical Trial
This is a randomized controlled trial with blinded assessor on the effects of aerobic exercise (walking)in patients with Ankylosing Spondylitis.
Ankylosing Spondylitis (AS) is a systemic inflammatory disease that affects mainly the spine
and compromises globally the physical capacity of the patients. Despite new advances in
pharmacological therapy, physiotherapy and exercise remain essential in the treatment of AS.
However, the literature lacks studies showing which types of exercises are more effective in
patients with AS.
This is a randomized controlled trial with the objective is to evaluate the effects of
aerobic training on functional capacity, mobility, disease activity, cardiopulmonary
capacity and cytokine levels (TNF, IL10, IL6 and IL1) in patients with AS.
The duration of the trial is 24 weeks with the first 12 weeks reserved to exercise programs.
The participants will be divided in two groups. The intervention group (IG) will perform
walking for 50 minutes plus global stretching 3 times a week for 12 weeks. The control group
(CG) will do only stretching exercises 3 times a week for 12 weeks.
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