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Clinical Trial Summary

With the increasing rise of outpatient surgery in orthopaedic procedures, the management of immediate postoperative pain has been a major topic investigated, with the use of a peripheral nerve block in combination with general anesthesia being a commonly accepted method. Foot and ankle procedures, which offer the choice of several anesthetic techniques, have increasingly been performed with this method predominantly through the combination of general anesthesia with a single-injection popliteal nerve block to reduce the substantial acute postoperative pain that often requires large opioid intake within the post-anesthesia care unit (PACU). However, as a single-injection peripheral nerve block resolves off shortly following surgery, major postoperative pain, termed "rebound pain", can also arise, and has the potential to be even greater than that of patients who do not receive any peripheral nerve block with general anesthesia. The purpose of this study is to evaluate the contribution of ropivacaine concentration (0.5% versus 0.25%) of the initial bolus in continuous popliteal nerve blocks toward the rebound pain phenomena, or the quantifiable difference in pain experienced during the initial time after block resolution, in foot and ankle surgeries.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04872322
Study type Interventional
Source Rothman Institute Orthopaedics
Contact
Status Enrolling by invitation
Phase Phase 3
Start date August 31, 2017
Completion date December 31, 2021

See also
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Enrolling by invitation NCT05425979 - Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks Phase 4
Terminated NCT01615939 - A Study Comparing Continuous Sciatic Nerve Block to Single Shot Sciatic Nerve Block Phase 4
Enrolling by invitation NCT06465992 - Liposomal Bupivacaine With Dexamethasone for Foot Surgery Phase 4
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Enrolling by invitation NCT04575688 - Periarticular Injection Versus Popliteal Block Phase 4
Recruiting NCT01546077 - Placement of Perineural Catheters in the Popliteal Region Phase 4
Recruiting NCT06309381 - Influence of Sensory Block Duration on Rebound Pain After Outpatient Foot Surgery Under Popliteal Sciatic Nerve Block.
Completed NCT04134962 - Evaluation of a New Tool for Measuring Hindfoot Alignment Under Load and in 3D.