Ankle Sprain Clinical Trial
Official title:
A Single Application of Electroacupuncture Improves Balance Greater Than Placebo Control in Subjects With Chronic Functional Ankle Instability
Introduction: Ankle sprains, the most common sports-related musculoskeletal injury, account
for approximately 25% of sports injuries. An estimated 40% of these individuals will
progress to develop chronic functional ankle instability (CFAI), which can significantly
affect athletic performance and activities of daily life. Stresses from the injury can
damage the ligaments, muscles, nerves and mechanoreceptors. It is widely accepted that ankle
proprioception is critical for balance and that individuals with CFAI demonstrate decreased
proprioception and altered muscular function, which impairs postural stability. The goal of
this study is to determine if a single application of electroacupuncture can have an
immediate positive outcome related to balance in individuals with CFAI.
Methods: This single blinded randomized trial will include 12 subjects receiving a single
application of electroacupuncture and 12 subjects in the placebo group receiving sham
electroacupuncture. Subjects aged 18-50 with a history of unilateral inversion ankle
sprain(s) and chronic symptoms of instability will be selected. Balance will be assessed
pre- and post-treatment using force plate data during a single-leg stance and via the Star
Excursion Balance Test (SEBT). GB-34 and GB-40 will be used for the experimental group and
non-traditional points on the medial aspect of the leg will be used for the sham
electroacupuncture group. Both will be connected to the electrical stimulation unit for 10
minutes. Results from this study may inform future research investigating the ability of EA
at decreasing the risk of ankle sprains, improving perceived stability, and reducing the
risk of subsequent degenerative changes.
A single application of electroacupuncture improves balance greater than placebo control in
subjects with chronic functional ankle instability
Specific Aim #1:
Evaluate the effect of a single application of electroacupuncture on center of pressure mean
total velocity in individuals with chronic functional ankle instability during single-leg
stance compared to placebo control.
H0: EA will not improve postural sway during single-leg stance compared to placebo control.
Specific Aim #2:
Describe the effects of a single application of EA compared to placebo on mean total
displacement, as well as the mediolateral and anterioposterior components during single-leg
stance for possible trends to inform hypothesis generation.
Specific Aim #3:
Correlate the results from the Star Excursion Balance Test with results of the single-leg
stance measures to inform hypothesis generation.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject)
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02246361 -
Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication
|
Phase 4 | |
| Completed |
NCT01438905 -
Effect of Joint Mobilization in the Treatment of Chronic Ankle Instability
|
N/A | |
| Recruiting |
NCT04095598 -
Computed Tomography With Stress Maneuvers for Evaluation of Distal Tibiofibular Syndesmosis Instability (CTMETS)
|
||
| Completed |
NCT01957215 -
Efficacy of Topical Indomethacin Patch Over Placebo in Ankle Sprain Pain Relief
|
Phase 4 | |
| Completed |
NCT01561365 -
Applicability of the Ottawa Ankle Rules
|
N/A | |
| Not yet recruiting |
NCT01446341 -
Cast Immobilization Versus Functional Therapy for Acute, Severe Lateral Ankle Sprains
|
N/A | |
| Completed |
NCT01255423 -
Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Applied 4 Times Daily in Subjects With Acute Ankle Sprain
|
Phase 3 | |
| Completed |
NCT00797368 -
Manual Therapy and Exercise Versus Home Exercises in the Management of Patients Status Post Ankle Sprain
|
N/A | |
| Completed |
NCT00573768 -
Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel in Patients With Acute Ankle Sprain
|
Phase 2 | |
| Completed |
NCT02324270 -
Safety and Efficacy of Generic Diclofenac Epolamine Acute Pain Due to Minor Ankle Sprain
|
Phase 3 | |
| Completed |
NCT02433964 -
Evaluation of Therapeutic Effects of LED (627 +/- 10nm) The Initial Phase of the Ankle Sprains Treatment
|
N/A | |
| Completed |
NCT00446797 -
Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain
|
Phase 4 | |
| Completed |
NCT02682303 -
Effect of Elastic Bandage on Balance in Chronic Ankle Instability
|
N/A | |
| Completed |
NCT02330198 -
Validation of the Foot and Ankle Ability Measure Tool in Finnish
|
N/A | |
| Completed |
NCT02097940 -
Influence of Sensorimotor Treatment in the Balance of Soccer
|
N/A | |
| Completed |
NCT01423513 -
Effects of Ankle Support on Muscle Activation and Function
|
N/A | |
| Completed |
NCT01449760 -
Ankle Sprain Rehabilitation With the Wii Balance Board
|
N/A | |
| Recruiting |
NCT02491736 -
Ketoprofen Gel vs Placebo in Children With Ankle Sprain
|
Phase 4 | |
| Recruiting |
NCT02945618 -
Neurocryostimulation for Acute Lateral Ankle Sprain
|
N/A | |
| Terminated |
NCT02729207 -
Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain
|
Phase 2 |