Ankle Fracture Clinical Trial
Official title:
The Impact of Liposomal Bupivicaine on Post-Operative Pain in Orthopaedic Trauma Surgery: A Double-Blind Prospective Randomized Control Trial
This study is a randomized controlled trial assessing pain control in ankle fractures repaired with open reduction and internal fixation. Patients are consented and enrolled pre-operatively, and randomized to either control or liposomal bupivacaine with bupivacaine administered intra-operatively.
This study is a prospective, randomized controlled trial assessing pain control in ankle
fractures repaired with open reduction and internal fixation. Patients are consented and
enrolled pre-operatively, and randomized to either control or liposomal bupivacaine with
bupivacaine administered intra-operatively. Patients are to remain blinded to the treatment
arm. The surgeon is non-blinded and administers the bupivacaine solution locally,
intra-operatively.
Patients pain scores and pain medication usage is documented. A trained research coordinator
contacts each patient at 24, 48, and 72 hours post-operatively to assess pain levels on a
visual analog scale (VAS) and pain medications taken. Patients return for followup at
standard intervals of 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post-operatively to
assess healing and functional outcomes. Patients are queried as to satisfaction with pain
control at 2 weeks post-operatively. The study will compare outcomes including pain levels,
pain medications taken, operating room (OR) and post-anesthesia care unit (PACU) times,
length of stay (LOS), satisfaction with pain control, clinical outcomes, and complication
rates.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01484535 -
Aspiration for Pain Relief Following Ankle Fracture
|
N/A | |
Completed |
NCT02779244 -
Early Weight Bearing for Unstable Ankle Fractures Undergoing Operative Stabilization
|
N/A | |
Completed |
NCT01561365 -
Applicability of the Ottawa Ankle Rules
|
N/A | |
Completed |
NCT02609347 -
Manual Therapy After Ankle/Hindfoot Fractures
|
N/A | |
Withdrawn |
NCT02863042 -
Is Deltoid Ligament Repair for Ankle Fracture Necessary?
|
N/A | |
Completed |
NCT01444144 -
Ankle Fracture Treatment in the Elderly
|
N/A | |
Completed |
NCT01729195 -
Ankle Syndesmosis Fixation by Antibiotic Releasing Bioabsorbable Screw
|
Phase 2 | |
Completed |
NCT01341015 -
Bedside Ultrasound in the Diagnosis of Ankle Fractures in Children
|
Phase 0 | |
Completed |
NCT01431560 -
Outcomes of Operative Treatment of Unstable Ankle Fracture - Comparison Between Metallic and Biodegradable Implants
|
Phase 4 | |
Unknown status |
NCT01654393 -
Triage Nurse Initiated Radiographs According to OAR
|
N/A | |
Completed |
NCT00132964 -
Brace Versus Casting in Pediatric Low Risk Ankle Fractures
|
N/A | |
Completed |
NCT02373254 -
NSAIDS Versus Opioids in Acute SER II Ankle Fractures
|
Early Phase 1 | |
Recruiting |
NCT02029170 -
Early Weightbearing Versus Non-weightbearing After Operative Treatment of an Ankle Fracture
|
N/A | |
Completed |
NCT02072135 -
Exparel and Ankle Surgery
|
N/A | |
Completed |
NCT01126398 -
Trauma Expectation Factor Trauma Outcome Measure
|
||
Completed |
NCT01493167 -
Study on Wood-plastic Composite for Circumferential Casting
|
N/A | |
Completed |
NCT02334618 -
Insole Sensor to Determine Optimal Limb Loading in the Rehabilitation of Ankle Fractures
|
N/A | |
Active, not recruiting |
NCT02032966 -
Surgical Versus Nonsurgical Treatment of Fibular Fractures: A Prospective Randomized Study
|
N/A | |
Not yet recruiting |
NCT01338129 -
The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture
|
N/A |