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Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty — IOTAA  

Infections Clinical Trial

Official title:
Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty

Clinical Trial Summary

The purpose of this study is to compare two different antibiotic regimens and techniques during total ankle arthroplasty (TAA). Primary Objective: Comparable levels of vancomycin will be found in bone, soft tissue, and systemic samples between patient groups. Secondary Objective: Compare 30 day and 90 day post-operative complication rates (infection) between the control (standard IV administration of vancomycin) vs the interventional group (intraosseous administration of vancomycin). The investigators hypothesize that there will be no difference in complication (infection) rates between groups.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06384651
Study type Interventional
Source The Methodist Hospital Research Institute
Contact Thomas C Sullivan, BS
Phone 346-238-1603
Email tsullivan@houstonmethodist.org
Status Recruiting
Phase Phase 4
Start date December 13, 2023
Completion date December 2027
View Details
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