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Anisometropic Amblyopia clinical trials

View clinical trials related to Anisometropic Amblyopia.

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NCT ID: NCT06286410 Recruiting - Clinical trials for Accommodation Disorder

Accommodation Response in Hypermetropic Anisometropia (ARIHA Study)

ARIHA
Start date: April 11, 2024
Phase: N/A
Study type: Interventional

Anisometropic amblyopia is when one eye has a much stronger glasses prescription than the other, causing poor vision in one eye, even with glasses, because the brain favours the better-seeing eye. With standard care treatment (glasses plus either patching or atropine drops given to the better seeing eye), 35% of children with anisometropic amblyopia do not have any significant visual improvements, and will have reduced vision in one eye for life. There is no consensus for the reasons why some children do not respond as well as others. Recent research using the Plusoptix PowerRefractor (PR3), which quickly measures eye focusing (accommodation), suggested that in children with anisometropic amblyopia, the focusing of the amblyopic eye might influence treatment success. However, such measurements weren't previously common due to equipment limitations in clinics. The investigators aim to use the non-invasive PR3 to assess accommodation in hypermetropic anisometropic amblyopia, at the University of Sheffield. This will be a two-phase study of children aged 4-10 years who have hypermetropic anisometropia. The investigators will recruit participants attending the Ophthalmology Department at Sheffield Children's NHS Foundation Trust (SCH). The investigators will take repeated measurements of accommodation at points during standard care treatment (phase 1) and conduct a pilot intervention study (phase 2) to determine whether adjusting glasses prescriptions based on accommodation responses with amblyopia treatment can improve vision in the weaker eye. The goal is to gather evidence to inform a future larger multicentre RCT to improve the visual outcomes for anisometropic amblyopic children in the future.

NCT ID: NCT05325021 Recruiting - Refractive Errors Clinical Trials

Correction of Anisometropic Amblyopia in Children.

Start date: April 2, 2022
Phase:
Study type: Observational

Anisometropic amblyopia among children in school age may affects quality of life and educational progress of children.

NCT ID: NCT04315649 Completed - Amblyopia Clinical Trials

Effect of 3D Movie Viewing on Stereopsis in Strabismus and / or Anisometropic Amblyops

Start date: September 16, 2021
Phase: N/A
Study type: Interventional

This study evaluates the effect of 3D movie viewing on stereopsis recovery in anisometropic and / or strabismus amblyopia and the satisfaction with the intervention.

NCT ID: NCT04313257 Completed - Amblyopia Clinical Trials

Monocular Action Video Game Treatment of Amblyopia

Start date: September 17, 2019
Phase: N/A
Study type: Interventional

This study evaluates the effectiveness of the monocular treatment with action video-games in comparison with the occlusion therapy alone in amblyopic patients, and the satisfaction with the different evaluated treatments.

NCT ID: NCT03342235 Withdrawn - Refractive Errors Clinical Trials

Excimer Laser Surgery for Anisometropic Amblyopia

ATS19
Start date: June 2020
Phase: N/A
Study type: Interventional

Study Objectives To compare the efficacy and safety of surgical treatment (PRK) versus non-surgical treatment of anisometropic amblyopia in children who have failed conventional treatment due to non-compliance or non-response. Synopsis of Study Design The study consists of two phases: 1. A Patching Run-In Phase during which all participants are treated for at least 8 weeks with continued refractive correction (with spectacles and/or contact lenses) and patching prescribed 42 hours per week (averaging 6 hours daily) until no further improvement over 2 consecutive visits at least 4 weeks apart or the vision no longer meets eligibility criteria. 2. A Randomized Trial Phase, beginning after no further VA improvement in the patching run-in phase and qualifying amblyopia is still present, during which the participant is assigned to either surgery with PRK and patching prescribed 2 hours per day or to non-surgical treatment with continued refractive correction (with spectacles and/or contact lenses) and patching prescribed 2 hours per day.