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Clinical Trial Details — Status: Active, not recruiting

Administrative data

NCT number NCT05576493
Other study ID # N-68-2022
Secondary ID
Status Active, not recruiting
Phase N/A
First received
Last updated
Start date August 11, 2022
Est. completion date December 1, 2023

Study information

Verified date August 2023
Source Cairo University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

comparing different types of cuclophotocoagulation with cataract extraction to cataract extraction and goniocynechiolysis in cases of chronic angle closure glaucoma


Description:

Evaluation of the safety of MP-TSCPC , CW-TSCPC and endoscopic cyclophotocoagulation when combined with phacoemulsification in cases with CACG Comparing the efficacy of the combined procedures in control of the IOP and the success rate versus lens extraction combined with synechiolysis


Recruitment information / eligibility

Status Active, not recruiting
Enrollment 88
Est. completion date December 1, 2023
Est. primary completion date October 1, 2023
Accepts healthy volunteers No
Gender All
Age group 20 Years to 70 Years
Eligibility Inclusion Criteria: - Patients between 20 to 70 years chronic angle closure glaucoma Exclusion Criteria: - Patients in acute attack of angle closure. - Patients with previous filtering surgery or cycloablative procedure

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
phaco+MP-TSCPC
The procedure starts with performing the cyclophotocoagulation using the Micropulse P3 device (IQ 810 Laser Systems; Iridex, Mountain View, CA, USA) at 2500 mW with a duration of 90 seconds in each hemisphere at a 31.3% duty cycle under local anesthesia and then performing phacoemulsification and IOL implantation.
phaco+TSCPC
The procedure starts with performing the cyclophotocoagulation using the IRIDEX's G probe device (IRIDEX Corp. Mountain View, CA, USA) at 1500 to2000 mW with a duration of 1500 ms applying about 15 shots in one hemisphere only under local anesthesia and then performing phacoemulsification and IOL implantation.
phaco+endocyclophotocoagulation
phacoemulsification will be done and endocyclophotocoagulation will be done after cataract extraction
phaco GSL
phacoemulsification will be done and then the angle is visualized by direct goniolens then the synechia are dissected by cohesive viscoelastic.

Locations

Country Name City State
Egypt Kasr Alainy Cairo

Sponsors (1)

Lead Sponsor Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary the percentage of intraocular pressure change measuring the intraocular pressure after 1M, 3M and 6M 6 Months
Secondary percent change of antiglaucoma medications the number of medication before and after the procedure 6 Months
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