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Angina Pectoris clinical trials

View clinical trials related to Angina Pectoris.

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NCT ID: NCT03657758 Not yet recruiting - Clinical trials for Coronary Artery Disease

Lesional Evaluation of High Risk Patients With Neoatherosclerosis Treated With Rosuvastatin and Eicosapentaenoic Acid Using Optical Coherence Tomography(OCT)[LINK IT TWO]

Start date: September 17, 2018
Phase: Phase 4
Study type: Interventional

This study aim is to evaluate the additional effect of eicosapentaenoic acid and dose up effect of rosuvastatin for neoatherosclerosis in coronary artery disease patients.

NCT ID: NCT03633890 Not yet recruiting - Clinical trials for Coronary Artery Disease

DaZhu Rhodiola Rosea Capsule for Coronary Artery Disease With Angina Pectoris

Start date: August 2018
Phase: Phase 4
Study type: Interventional

This study aims to evaluate the efficacy and safety of traditional Chinese medicine DaZhu Rhodiola Rosea Capsule for treatment of coronary artery disease by observing angina symptoms, exercise capacity, and quality of life.

NCT ID: NCT03179618 Not yet recruiting - Unstable Angina Clinical Trials

Research on the Clinical Effect of Xuefu Zhuyu Decoction in Treating Unstable Angina.

Start date: July 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the clinical efficacy of Xuefu Zhuyu Decoction in the treatment of unstable angina pectoris. All of the patients will be divided into 2 arms randomly. One of the arms will be treated by conventional western medicine, the other one will be treated by Xuefu Zhuyu Decoction at the base of conventional western medicine.

NCT ID: NCT03179527 Not yet recruiting - Unstable Angina Clinical Trials

Research on the Clinical Effect of Shuanghe Decoction in Treating Unstable Angina.

Start date: July 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the clinical efficacy of Shuanghe Decoction in the treatment of unstable angina. All of the patients will be divided into 2 arms randomly. One of the arms will be treated by conventional western medicine, and the other one will be treated by Shuanghe Decoction at the base of conventional western medicine.

NCT ID: NCT03179514 Not yet recruiting - Unstable Angina Clinical Trials

Effect of Gualou Xiebai Banxia Decoction With Danshen Decoction in Treating Unstable Angina.

Start date: July 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the clinical efficacy of Gualou Xiebai Banxia Decoction compounded with Danshen Decoction in the treatment of unstable angina pectoris. All of the patients will be divided into 2 arms randomly. One of the arms will be treated by conventional western medicine, the other one will be treated by Gualou Xiebai Banxia Decoction compounded with Danshen Decoction at the base of conventional western medicine.

NCT ID: NCT03171597 Not yet recruiting - Unstable Angina Clinical Trials

Research on the Clinical Effect of Effective Prescription in Treating Unstable Angina.

Start date: August 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the clinical efficacy of the famous prescription in the treatment of unstable angina pectoris. All of the patients will be divided into 4 arms according to their syndrome type. One of the arms will be treated by conventional western medicine, the other three will be treated by different Chinese herbal medicine prescription at the base of conventional western medicine.

NCT ID: NCT03155971 Not yet recruiting - Clinical trials for Stable Angina Pectoris

PCB for Long De Novo Lesions of Main Coronary Arteries (D-Lesion Long Trial)

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

This study evaluates the Efficacy and Safety of Paclitaxel-Coated Balloon Catheter in Patients With Diffuse Long De Novo Lesions of Main Coronary Arteries.

NCT ID: NCT02928094 Not yet recruiting - Angina, Stable Clinical Trials

Ad5FGF-4 In Patients With Refractory Angina Due to Myocardial Ischemia

AFFIRM
Start date: January 1, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether a single intracoronary infusion of an adenovirus serotype 5 virus expressing the gene for human fibroblast growth factor-4 (Ad5FGF-4) is effective in improving angina-limited exercise duration, angina functional class, frequency of angina attacks, frequency of nitroglycerin usage, and quality of life. Half of the study participants will receive Ad5FGF-4, and half will receive placebo. The primary endpoint is the change from baseline to Month 6 in Exercise Tolerance Test (ETT) duration. Long-term safety of Ad5FGF-4 will also be assessed.

NCT ID: NCT02802046 Not yet recruiting - Angina Pectoris Clinical Trials

Evaluation of the Correlation Between the Coronary Stenosis Degree With FFRCT and the Grade of Stable Angina Pectoris

Start date: January 2017
Phase: N/A
Study type: Observational

Angina pectoris is the most common clinical manifestation of coronary heart disease(CHD), which is the main feature of chest pain caused by transient myocardial ischemia. Chronic stable angina pectoris is the degree, frequency, nature and cause of angina pectoris in patients with no significant change in a few weeks. The disease incidence is complex, difficult to diagnosis and treatment, clinical should be combined with various inspection methods for diagnosis and differential diagnosis. Fractional flow reserve of computerized tomographic scanning (FFRCT ) allows computerized tomographic scanning(CT) to scan the determination of coronary blood flow and blood pressure in the heart at rest and hyperemia, but no need to additional check or drugs. This technique has been used for noninvasive fractional flow reserve (FFR) in the calculation, assuming normal artery, calculated by the ratio of the maximum blood flow and blood flow of coronary artery stenosis of an artery. Along with the development and progress of computational fluid dynamics, in the resting state by computed tomographic angiography of coronary artery(CCTA) image data based, simulation of coronary artery maximal hyperemia and according to the 3-dimensional model of the traditional method of reconstruction of coronary arterial tree and ventricular muscle structure, and in order to calculated coronary blood flow and pressure. FFRCT is a novel non-invasive examination method, using computed tomographic angiography of coronary artery image data can be calculated FFR, and preliminary study proved that it has a high degree of correlation with traumatic FFR. Therefore, this study aims to evaluate the correlation between the degree of coronary stenosis and the grading of angina pectoris by noninvasive means --FFRCT, in order to provide a new idea for the diagnosis and differential diagnosis of coronary heart disease.

NCT ID: NCT02694848 Not yet recruiting - Angina Clinical Trials

Clinical Study of Combination Therapy for Angina of Coronary Heart Disease With Aspirin and Salvianolate Injection

Start date: February 2016
Phase: Phase 4
Study type: Interventional

To evaluate the therapeutic evaluation of combination therapy with aspirin and salvianolate injection based on the population pharmacokinetics and TEG.A prospective, multicenter, randomized, controlled clinical trial is used.A total of 120 patients will be recruited and will be divided into three groups,respectively salvianolate injection group,aspirin group and salvianolate injection and aspirin group,and the course of treatment is 10 days.