Psychotherapy for Intermittent Explosive Disorder

Anger Clinical Trial

Official title:

Individual Cognitive Behavioral Psychotherapy for Intermittent Explosive Disorder

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00667212
• Other study ID #: 15143A
• Status: Completed
• Phase: Phase 2
• First received: April 24, 2008
• Last updated: June 11, 2013
• Start date: August 2006
• Est. completion date: December 2010

Study information

• Verified date: December 2010
• Source: University of Chicago
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

The goal of this study is to examine the effectiveness two forms of psychotherapy (also known as "talk therapy" ) for individuals with anger and aggression problems. Anger and aggression are everywhere - on the road, in the schools, at little league games, at home, and at work. In this study we are testing usefulness of anger management techniques in reducing symptoms of Intermittent Explosive Disorder (IED) and impulsive, aggressive behavior.

Description:

Qualified participants will be randomly assigned to 12 1-hour sessions of either cognitive-behavioral therapy or supportive psychotherapy.

Participation in this study will require 16 visits over approximately 4 months with 3 follow-up sessions over a 12 month period. Therapy is provided at no cost and each study participant will receive a comprehensive psychological assessment. Two types of talk therapy are being offered in this study. One form of therapy focuses on thought and behaviors associated with anger and aggression. This type of therapy is known as cognitive behavioral therapy. The other type of therapy focuses on the individuals' feeling about their anger /aggression and the situations that lead to this anger. This is known as supportive therapy. The form of therapy you are given will be randomly determined (like by flipping of a coin).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: December 2010
• Est. primary completion date: December 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 55 Years

Eligibility

Inclusion Criteria:

• Have problems with anger, temper outbursts, being irritable, getting in trouble at work or at home because of impulsive/aggressive behavior.

• Between the ages of 18 and 55.

• Meet other eligibility requirements as outlined by the research protocol.

Exclusion Criteria:

• CHECK ON THIS

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Anger
• Impulse Control Disorders
• Intermittent Explosive Disorder

Intervention

Behavioral:
• Cognitive Behavioral Therapy
Twelve weekly therapy sessions, approximately one hour each in duration
• Supportive Psychotherapy
Twelve weekly therapy sessions, approximately one hour each in duration

Locations

Country	Name	City	State
United States	University of Chicago	Chicago	Illinois

Sponsors (1)

Lead Sponsor	Collaborator
University of Chicago

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Overt Aggression Scale - Modified (OASM)		Screen Visit, Pre-Therapy visit, Therapy sessions 2, 4, 6, 8, 12, Post-Therapy Visit, 3, 6, and 12-month Follow-Up Vists	No
Primary	State-Trait Anger Expression Inventory - Trait Anger Scale [STAXI-T]		Pre-Therapy visit, Therapy session 7, Post-Therapy visit	No
Primary	Intermittent Explosive Disorder Interview		Diagnostic Interview, Post-Therapy Visit (Modified), 3, 6, and 12-month Follow-Up vists (modified)	No
Secondary	Behavioral aggression measures (Taylor Aggression Paradigm [TAP], Point Subtraction Aggression Paradigm [PSAP])		Pre-Therapy Visit, Post-Therapy Visit, 3, 6, and 12-month Follow-Up visits	No