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Lycopene Following Aneurysmal Subarachnoid Haemorrhage — LASH  

Subarachnoid Hemorrhage Clinical Trial

Official title:
Acute Oral Lycopene Therapy on Cerebral Autoregulation and Delayed Ischaemic Deficits Following Aneurysmal Subarachnoid Haemorrhage (LASH): A Randomized Controlled Trial

Clinical Trial Summary

In this study the investigators wish to explore the potential neuroprotective effects of acute oral supplementation of lycopene, a natural anti-oxidant derived from tomatoes, on cerebral vasospasm and autoregulation, and examine whether any improvements translate into a reduction of biochemical markers of vascular injury and inflammation a decrease in the prevalence of secondary strokes following subarachnoid haemorrhage.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00905931
Study type Interventional
Source University of Cambridge
Contact Karol P Budohoski, MD
Phone (0044)1223331763
Email kpb26@cam.ac.uk
Status Not yet recruiting
Phase Phase 2
Start date September 2010
Completion date October 2012
View Details
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