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Aneuploidy Rates of in Vitro Matured Oocytes — IVM  

Aneuploidy Clinical Trial

Official title:
Aneuploidy Rates of in Vitro Matured Oocytes

Clinical Trial Summary

In general, nearly 85% of retrieved oocytes are mature and reproductively useful after the retrieval, whereas the remaining percentage are still at metaphase I or germinal vesicle stage (MI: 4% and GV: 11 %, respectively).

The objective of our study is to assess if immature oocytes co-cultured with autologous cumulus cells is a safer strategy than just leaving the oocytes in standard culture.

Clinical Trial Description

Under controlled ovarian stimulation, patients with normal functional ovarian reserves produce a good number of oocytes at retrieval. However, in addition to quantity, oocyte maturity is an important variable for the success of reproductive technologies. In general, nearly 85% of retrieved oocytes are mature and reproductively useful, whereas the remaining percentage are still at metaphase I or germinal vesicle stage (MI: 4% and GV: 11 %, respectively). Due to the limited expectations held for in vitro maturation in said stimulated cycles, the rescue of immature oocytes is not widely used in current clinical practice and these oocytes are usually discarded due to the possibility of abnormal embryonic development or an increased rate of abortion.

The objective of our study is to assess if immature oocytes co-cultured with autologous cumulus cells is a safer strategy than just leaving the oocytes in standard culture. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03860064
Study type Observational
Source IVI Barcelona
Contact
Status Completed
Phase
Start date March 27, 2019
Completion date September 30, 2019
View Details
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