Anesthesia of Mucous Membrane Clinical Trial
Official title:
Comparison of Efficacy of Two Topical Anesthetics: Benzocaine Versus Pliaglis for Control of Pain Associated With Dental Needle Insertion in the Palate, A Double Blind Study
This project will be a double blind study comparing the efficacy of two different topical
anesthetics used to reduce the pain associated with insertion of dental needles on the
palatal mucosa. The two topical anesthetics being compared are 20% Benzocaine, and Pliaglis.
In order to complete a number of different dental procedures it is often necessary to
provide local anesthesia of the palate. Intraoral injections into the palatal mucosa are
often uncomfortable and even painful. In an effort to increase patient comfort, a topical
anesthetic is often used prior to the injection. Test subjects undergoing routine endodontic
treatment on maxillary teeth will have a 27- gauge dental needle inserted into the mucosa of
the hard palate as part of the initial step in standard local anesthetic injection. At the
injection site and prior to the needle stick, the mucosa will be topically anesthetized by
using one of the two different test compounds (Benzocaine or Pliaglis). After the injection
patients will be asked to score the level of discomfort associated with the needle stick.
The purpose of the project is to determine if there is a clinical difference in the level of
pain felt upon needle stick, between the two different topical anesthetics.
The Efficacy of the topical anesthetics will be determined by how much pain the patient felt (using a Heft-Parker pain analog scale) upon needle penetration. ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
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