The Comparison Of Nerve Blocks In Cesarean Delivery

Anesthesia, Obstetrical Clinical Trial

Official title:

The Comparison Of Different Nerve Blocks For Postoperative Analgesia In Cesarean Delivery: A Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03333902
• Other study ID #: [2016]123
• Status: Completed
• Phase: N/A
• Start date: December 1, 2017
• Est. completion date: August 30, 2018

Study information

• Verified date: January 2019
• Source: First Affiliated Hospital, Sun Yat-Sen University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to investigate the effect of different kinds of popular peripheral nerve blocks for postoperative analgesia after cesarean delivery is completed, compared with traditional epidual analgesia.

Description:

Visual Analogue Scale (VAS) and morphine consumption was adopted to evaluate the pain relief.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 102
• Est. completion date: August 30, 2018
• Est. primary completion date: June 30, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 24 Years to 40 Years

Eligibility

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) physical status I or II

• weight from 50 to 70 kilogrammes

• a normal singleton pregnancy

• =37 weeks gestation

Exclusion Criteria:

• congenital coagulopathy

• anatomic abnormalities

• localized skin infection

• allergy to any of the drugs used

Related Conditions & MeSH terms

• Anesthesia, Obstetrical

Intervention

Procedure:
• QLB
QLB, quadratus lumborum block.
• Intravenous patient controlled analgesia (PCA)
Intravenous patient controlled analgesia (PCA) pump was used to supply additional analgesia and removed 48 h post-operationally.

Locations

Country	Name	City	State
China	The First Affiliated Hospital of Sun Yat-Sen University	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Feng Xia

Country where clinical trial is conducted

China, 

References & Publications (1)

Blanco R, Ansari T, Girgis E. Quadratus lumborum block for postoperative pain after caesarean section: A randomised controlled trial. Eur J Anaesthesiol. 2015 Nov;32(11):812-8. doi: 10.1097/EJA.0000000000000299. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the change trend of Visual Analogue Scale (VAS) at rest and movement	The purpose is to view the change of the level of pain assessed by subjects at adjacent time points. We would set 0, 4, 6, 12, 24, 48 hours postoperatively as observational time points.	0-48 hours postoperatively
Secondary	total morphine consumption	total morphine consumption	0-48 hours postoperatively
Secondary	complications	nausea, vomiting, retention of urine, lower limb weakness, etc.	0-48 hours postoperatively