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Clinical Trial Summary

Although the exact mechanism remains unknown, the association of pregnancy and decreased local anesthetic requirement is clear. demonstrated that more local anesthetic is required for cesarean section under combined spinal-epidural anesthesia in preterm compared with term patients.


Clinical Trial Description

However, in pregnant patients, venous engorgement is prominent in the supine but not the lateral position, which suggests direct compression of the inferior vena cava by the gravid uterus. Second, an increase in intraabdominal pressure may affect the retroperitoneal area and may cause inward movement of soft tissue in the intervertebral foramina. Recent magnetic resonance imaging studies in pregnant patients, although without intraabdominal pressure measurements, suggested the latter because they showed limited contact of engorged veins along the dural sac which may therefore not be responsible for compression of the dura.

If elevated intraabdominal pressure contributes to high anesthetic spread during pregnancy, one would expect a relationship between intraabdominal pressure and maximum sensory block level. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03164096
Study type Interventional
Source Assiut University
Contact
Status Recruiting
Phase Phase 4
Start date June 1, 2017
Completion date December 10, 2018

See also
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Completed NCT05091294 - The Effect of Injection Rate of Local Anesthetic in Caesarean Section N/A
Completed NCT04205344 - Subarachnoid Bupivacaine in Obese Patients Undergoing Cesarean Delivery Phase 4
Completed NCT03333902 - The Comparison Of Nerve Blocks In Cesarean Delivery N/A