Anesthesia, General Clinical Trial
Official title:
Quantitative Frontal Electroencephalography (EEG) and Postoperative Emergence Delirium Following General Anesthesia in Children: a Prospective Observational Study
Most drugs used in general anesthesia work on various receptors in the human brain, causing
unconsciousness, loss of memory, and loss of reflection of the autonomic nervous system.
After the anesthesia, baseline physiological function will be attained by administration of
some reversal drugs or as the time goes by. In this process, various side effects may occur.
Emergence delirium (ED) is a representative behavioral disturbance after general anesthesia
in children and that can cause several problems during the recovery period. Previous EEG
studies reported that this phenomenon is related to hyperexcitation of the brain, and
occurrence of epileptiform discharges during anesthesia induction may indicate an increased
vulnerability for the development of a functional brain disorder in these children.
However, to the best of our knowledge, there is no studies concern evaluating quantitative
EEG parameters for prediction of this postoperative negative behavior in children.
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