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Anesthesia, General clinical trials

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NCT ID: NCT02492282 Completed - Anesthesia, General Clinical Trials

Evaluation of a Novel Closed-loop Propofol and Remifentanil System Guided by Bispectral Index Compared to a TCI Open-loop System

Start date: June 2015
Phase: Phase 3
Study type: Interventional

Closed loop system in intravenous anesthesia is more effective to maintain depth of anesthesia compared with manual system open, it is unclear what driver and variables to achieve this goal be more physiological; in the literature doesn´t exist studies showing that the closed-loop system for both hypnotic and opioid is better than the controlled pharmacokinetic models and open loop system (target controlled infusion-TCI) to maintain anesthetic depth. In addition, the infusion of the opioid lacks physiological controllers in closed loop. Thus, a system was designed for intravenous anesthesia in closed loop for propofol as hypnotic based on neuromonitoring bispectral index as anesthetic depth, and was integrated an additional closed system for remifentanil using hemodynamic variables and control algorithm associated with bispectral index. The purpose of this study is to determine the therapeutic effectiveness of a new system of administration of intravenous anesthesia in closed loop to maintain a depth of anesthesia compared to an open loop system TCI.

NCT ID: NCT02379546 Completed - Anesthesia, General Clinical Trials

The Effect of Anaesthesia Depth on Oculo-cardiac Reflex

Start date: August 2013
Phase: Phase 4
Study type: Interventional

This study was designed to determine the effect of the depth of anesthesia on the oculocardiac reflex (OCR) during pediatric strabismus surgery.

NCT ID: NCT01899248 Completed - Anesthesia, General Clinical Trials

The Effect of Inhalation Agent on the QTc Interval During Liver Transplantation: Sub Study (NCT01886664)

Start date: December 2012
Phase: N/A
Study type: Observational

The purpose of this study is to assess the effects of inhalation agent on corrected QT interval duration during liver transplantation.

NCT ID: NCT01865643 Completed - Anesthesia, General Clinical Trials

A Comparison of Two GlideScope Intubation Techniques

Start date: May 2013
Phase: N/A
Study type: Interventional

The aim of this study is to compare the hemodynamic response to tracheal intubations using the standard technique versus the alternative GS intubation technique. As secondary outcomes the investigators will analyze procedure time, success rate and injury rate. The investigators hypothesize that the alternative intubation technique will have a shorter procedure time and lower injury rate when compared to the standard technique of GS intubation.

NCT ID: NCT01715857 Completed - Anesthesia, General Clinical Trials

Clinical Practice of Inhalation Anesthesia With Sevoflurane in China

Start date: July 2012
Phase: N/A
Study type: Observational

Until recently, there was a lack of understanding and consensus among Chinese anesthesiologists how they should practice general anesthesia with volatile anesthetics, since there was no standard of inhalation practice. In August 2011, the Anesthesiology branch of the Chinese Medical Association launched the first version of Chinese Consensus of Standard Clinical Practice for Inhalation Anesthesia (Consensus) in order to standardize the practice in China. The proposed registry is aimed to evaluate the current inhalation practice one year after the Consensus has been released, and related patient outcome. This registry evaluated sevoflurane anesthesia, including screening, induction, maintenance, emergence, and follow-up within 24 hours post-operation.

NCT ID: NCT01650961 Completed - Anesthesia, General Clinical Trials

The Effect of Palonosetron on the QTc Interval During Perioperative Period

Start date: July 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effects of palonosetron on corrected QT interval duration during and after general anesthesia.

NCT ID: NCT01584570 Completed - Anesthesia, General Clinical Trials

The Effects of Dexmedetomidine and Tracheal Intubation on Heart Rate Variability and QTc Interval

Start date: January 1, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate effect of dexmedetomidine and tracheal intubation on heart rate variability and QTc interval.

NCT ID: NCT01467167 Completed - Anesthesia,General Clinical Trials

Utility of the Smart Pilot View in Clinical Practice: A Two Center Prospective Observational Study

Start date: October 2011
Phase:
Study type: Observational

Recently, a new software program for anesthesia has been developed, called Smart Pilot View. This program monitors the patient, the anesthetic drugs given, and the calculated depth of the anesthesia. The purpose of this study is to determine whether the use of this program improves the quality of anesthesia.

NCT ID: NCT01323049 Completed - Anesthesia, General Clinical Trials

Comparison of Spontaneous Ventilation Time in Air Without Desaturation After Positive Pressure Extubation Versus Aspiration Extubation When Awakening From General Anesthesia

Start date: March 2012
Phase: N/A
Study type: Interventional

The primary objective is to show that positive pressure extubation improves oxygenation immediately after extubation compared to extubation via "aspiration" by evaluating and comparing the onset time of desaturation during spontaneous ventilation during awakening following general anesthesia.

NCT ID: NCT01282203 Completed - Anesthesia, General Clinical Trials

Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Required General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on Cardiovascular System in Common Clinical Practice

SEVOPROTECTION
Start date: July 2011
Phase: N/A
Study type: Observational

The main objective of this post-marketing observational study is to collect data from the use of general anesthesia in patients undergoing any surgery to create local recommendations. These data will be based on the evaluation of volatile induction and maintenance anesthesia (VIMA) with Sevorane® (sevoflurane) in adult patients requiring general anesthesia for surgery in terms of quality of anesthesia and its influence on cardiovascular system in common clinical practice in Kazakhstan.