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Anesthesia, Epidural clinical trials

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NCT ID: NCT02197403 Recruiting - Alcohol Drinking Clinical Trials

Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker

DEX
Start date: December 2013
Phase: Phase 4
Study type: Interventional

1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3. Dexmedetomidine, α2 receptor agonist, may provide adequate sedation in heavy alcohol drinkers

NCT ID: NCT01260051 Completed - Breast Feeding Clinical Trials

Intrapartum Epidural Fentanyl/Bupivacaine Analgesia, Infant Feeding Behavior, & Breast-Feeding Outcomes

Start date: March 2010
Phase:
Study type: Observational

Currently, no clear consensus exists regarding the effect of epidural anesthesia upon breast-feeding. In theory, epidurals may increase breast-feeding failure via inadequate maternal milk production, deficiencies in neonatal neurobehavior, or both, but most studies have failed to separate these potential mechanisms. The present study examines whether epidural duration correlates with 1) likelihood of breast-feeding at hospital discharge and 2) neonatal neurobehavioral deficits in feeding, as measured by the L&A components of the standardized, validated LATCH scoring system.

NCT ID: NCT00394459 Completed - Clinical trials for Anesthesia, Epidural

Safety of Two Epidural Catheters in Thoracic Epidural Anaesthesia (TEA)

Start date: April 2005
Phase: Phase 4
Study type: Interventional

Primary Objective: The primary objective is to demonstrate that the safety of Perifix New is non-inferior to using Perifix Standard when applied for thoracic epidural anaesthesia. Primary Endpoint: Incidence of spontaneous paraesthesia during catheter insertion Secondary Objectives: The secondary objectives are to determine the safety and performance of the investigational product: frequency of inadvertent vascular cannulation, difficulties involved in insertion and removal of the catheter, other safety features and data for the evaluation of handling characteristics. Title: Randomised, prospective, single-blind, controlled, study on the safety of two epidural catheters in patients undergoing surgery under thoracic epidural anaesthesia Investigational Product: Perifix Epidural Anaesthesia Catheter Test Product: Perifix New Reference Product: Perifix Standard Number of Sites and Countries: 1 site in The Netherlands Indication: Thoracic epidural anaesthesia Study Design: Randomised, prospective, single-blind, controlled study in 1 study center, phase IV Perifix New and Perifix Standard meet all the appropriate provisions of the relevant legislation implementing European Directives (both have CE-marking). Study Duration: 2 year duration Study Start: March-April 2005 Sample Size: n = 2*70 patients

NCT ID: NCT00223002 Completed - Analgesia, Epidural Clinical Trials

Chlorhexidine Versus Povidone-Iodine for Prevention of Epidural Needle Contamination in the Parturient

Start date: November 2004
Phase: N/A
Study type: Interventional

Infection after epidural catheter placement is fortunately rare. When it does happen, the affected person can become seriously ill. This study examines which skin disinfectant, chlorhexidine or povidone-iodine, decreases the number of bacteria that can be grown from the skin washed with each disinfectant prior to placing an epidural catheter for pain control in labour.