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Clinical Trial Summary

The aim of the study is to assess the impact of pentoxifylline administration on the modulation of hyporesponsiveness to erythropoietin stimulating agents in hemodialysis patients


Clinical Trial Description

this is a prospective, randomized, controlled study to assess the impact of pentoxifylline administration on the modulation of hyporesponsiveness to erythropoietin stimulating agents in hemodialysis patients by determining several outcomes from the intervention and control groups at the end of the study.These outcomes include;the difference in hemoglobin and hematocrit concentration , the difference in inflammatory markers tumor necrosis factor Alpha (TNF-α), interleukin-1 Beta (IL-1β),the difference in the dosage of erythropoiesis stimulating agents ,and The erythropoietin stimulating agents (ESA) resistance index (ERI). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03800433
Study type Interventional
Source Ain Shams University
Contact Radwa M Elmetwaly, Bachelor
Phone 00201065371016
Email radwa_mohm@yahoo.com
Status Not yet recruiting
Phase Early Phase 1
Start date October 2019
Completion date April 2020

See also
  Status Clinical Trial Phase
Terminated NCT03401710 - Erythropoietin Role in Acute Kidney Injury N/A