Autologous Umbilical Cord Blood Transfusion for Preterm Neonates

Status Withdrawn

Clinical Trial Summary

This is a pilot study to test feasibility of collection, preparation and infusion of a baby's own (autologous) umbilical cord blood in the first 14 days after birth if the baby is born premature <35 weeks of gestation.

Clinical Trial Description

In Egypt, 12-15.8% of live neonates are low birth weight and it is estimated that about one third of such infants are preterm [1] (UNICEF, 2001). In a study that Campbell et al. (2004) conducted in Egypt, the neonatal mortality rate was estimated to be 25 per 1000 live births. prematurity was considered the main cause of neonatal deaths (39%), followed by asphyxia (18%), infection (7%), especially in the late neonatal period, and congenital malformations (6%). A substantial proportion (29%) could not be classified [2]. In developing countries, prematurity was the main cause of early neonatal deaths (62%)[3] Autologous cord blood transfusion will be safe, and cheap. The preterm neonates need transfusion of whole blood or any of its components at a time during NICU admission. ;

Study Design

Related Conditions & MeSH terms

Anemia of Prematurity
Cerebral Hemorrhage
Hemorrhage
Intraventricular Hemorrhage
Premature Birth
Prematurity
Respiratory Distress Syndrome
Respiratory Distress Syndrome, Adult
Respiratory Distress Syndrome, Newborn

Clinical Trial Details

NCT number	NCT01121328
Study type	Interventional
Source	Ain Shams University
Contact
Status	Withdrawn
Phase	Phase 1
Start date	July 2011
Completion date	September 2014

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT06168149` - The Relationship of Fetal Lung Elastography Values With the Development of Respiratory Distress in Cases of Preterm Labor
Recruiting	`NCT03670732` - CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure	N/A
Recruiting	`NCT02901652` - NIPPV and nBiPAP Methods in Preterm Infants With Respiratory Distress Syndrome	N/A
Completed	`NCT02249143` - Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants	N/A
Suspended	`NCT01852916` - NHFOV Versus NCPAP to Prevent Exubation Failure	N/A
Completed	`NCT00208039` - Pilot Trial of Surfactant Booster Prophylaxis For Ventilated Preterm Neonates	N/A
Recruiting	`NCT03510169` - Use of Gentle Synchronized Negative Pressure in Helping Babies Breathe	N/A
Completed	`NCT00004494` - Phase I Study of Vasoactive Intestinal Peptide in Patients With Acute Respiratory Distress Syndrome and Sepsis	Phase 1
Completed	`NCT00006058` - Study of the Pathobiology of Bronchopulmonary Dysplasia in Newborns	N/A
Completed	`NCT00004805` - Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden Death	N/A
Completed	`NCT03292562` - A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation	N/A
Completed	`NCT05948332` - Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxygenation
Completed	`NCT05038514` - The Effect of Music Therapy in COVID-19 Patients Given Prone Position	N/A
Active, not recruiting	`NCT04079829` - Postoperative Respiratory Abnormalities
Completed	`NCT05462509` - Feasibility of Use of the PATH bCPAP and Oxygen Blenders Device With Neonates in Uganda	N/A
Active, not recruiting	`NCT03808402` - The Effect of Surfactant Dose on Outcomes in Preterm Infants With RDS
Completed	`NCT01812681` - Cord Blood 25(oh)-Vitamin D Level in Preterm Infants and Associated Morbidities	N/A
Not yet recruiting	`NCT01440868` - Sustained Lung Inflation in the Delivery Room in Preterm Infants at High Risk of Respiratory Distress Syndrome	N/A
Completed	`NCT01517958` - Lung Ultrasound to Diagnose Transient Tachypnea of the Newborn (TTN) Versus Respiratory Distress Syndrome (RDS) in Neonates	N/A
Completed	`NCT01222247` - Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial	Phase 3