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Androgens clinical trials

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NCT ID: NCT05288166 Active, not recruiting - Prostatic Neoplasms Clinical Trials

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)

CYCLONE 3
Start date: April 14, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse. Participation may last approximately 60 months.

NCT ID: NCT04807231 Recruiting - Testosterone Clinical Trials

Comparison Between Calculated Bioavailable Testosterone Level With Radio-immunoassay Result.

TESTOBIO
Start date: March 11, 2021
Phase:
Study type: Observational

Currently, the gold standard to obtain bioavailable testosterone results is radioimmunoassay (RIA). However, this assay requires specific equipment. Giton in 2006 proposed an optimized calculation of the Vermeulen equation, the results of which seem to be well correlated with those obtained by RIA. The aim of this study is to determine if the bioavailable testosterone levels determined by both methods are similar in order to replace the usual RIA assay of bioavailable testosterone by this calculation.

NCT ID: NCT02434562 Completed - Hypogonadism Clinical Trials

Development and Validation of in Vitro Cell-based Bioassays for Nuclear Receptor Activation

Start date: April 2012
Phase: N/A
Study type: Observational

This is a prospective biobank set up to collect serum from patients with disorders associated with changes in androgens, estrogens or sex hormone-binding globulin (SHBG), before and/or after treatment.

NCT ID: NCT00434824 Completed - Hypogonadism Clinical Trials

Effects of Andriol Testocaps in Symptomatic Late-Onset Hypogonadism (43203)

Start date: November 2001
Phase: Phase 2
Study type: Interventional

In this study we have evaluated the effects of three different doses of oral testosterone undecanoate in aging men presenting with a combination of symptoms suggestive of hypogonadism and low blood levels of the male hormone testosterone. Specifically, we have studied the effects on: - symptoms suggestive of low testosterone levels - blood testosterone and other hormone levels - bone mass - muscle mass and fat mass - muscle strength - prostate - lipids, hematocrit