ANCA Associated Vasculitis Clinical Trial
Official title:
Multicenter Cohort Study of ANCA-associated Small Vasculitis in Hunan Province of China
This study aimed to explore the incidence of Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) progression and its association with adverse consequences. It will enroll approximately 500 AAV patients in Hunan province of China and follow-up for at least 5 years. Demographic characteristics, clinical and laboratory data will be collected at baseline and every follow-up. The principal clinical outcomes of the study consist of end stage renal disease (ESRD) and death.
The study is a multicenter prospective cohort study, aimed to explore the incidence of AAV and its progression and association with adverse consequences. The study will establish a baseline cohort of 500 AAV patients in Hunan province of China. The follow-up will be conducted for at least 5 years until death or starting renal replacement therapy or dropout. Their demographic characteristics, clinical data, laboratory and imaging examinations will be collected at baseline and every follow-up. The baseline visit includes the following items: detailed demographics, medical and family history, medication history, health behaviors, physical activity, and anthropometric measures. The laboratory parameters of chemistry test. After the baseline visit, participants will return annually for follow-up visits and evaluation. The evaluating items of follow-up visits are similar to the baseline visit, and sample collection. The principal clinical outcomes of the study can be broadly categorized as end stage renal disease and death. Death is further clarified as cardiac, infectious, renal, others, or unknown. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06462768 -
Neutrophil Extracellular Traps in Different Forms of Systemic Sclerosis
|
||
Recruiting |
NCT03942887 -
Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis
|
Phase 3 | |
Not yet recruiting |
NCT06420154 -
The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases
|
Early Phase 1 | |
Completed |
NCT04895878 -
Patients With Co-occurrence of ANCA Vasculitis and Sjögren Syndrome
|
||
Completed |
NCT00293072 -
Pilot Study of Rituximab Therapy for Systemic Lupus Erythematosus (SLE) and Vasculitis
|
Phase 2 | |
Recruiting |
NCT04664465 -
PRediction Of DIverse Glucocorticoids toxIcity OUtcomeS
|
||
Terminated |
NCT05376319 -
PR3-AAV Resilient Remission or PRRR
|
Phase 2 | |
Recruiting |
NCT04737343 -
Comparison of the Efficacy of Leflunomide and Azathioprine for the Maintenance Therapy of ANCA Associated Vasculitis
|
N/A | |
Recruiting |
NCT05962840 -
Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM)
|
Phase 4 | |
Suspended |
NCT03906227 -
Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis
|
N/A | |
Not yet recruiting |
NCT06152172 -
CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101
|
Phase 1 | |
Not yet recruiting |
NCT05946564 -
A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO Trial
|
Phase 3 | |
Recruiting |
NCT04923074 -
the Application of Diffusion Tensor Imaging in the Evaluation of Peripheral Neuropathy in ANCA Associated Vasculitis
|
||
Active, not recruiting |
NCT01633476 -
CMV Modulation of the Immune System in ANCA-associated Vasculitis
|
Phase 2 | |
Not yet recruiting |
NCT05416723 -
Occupational and Environmental Origins of ANCA Vasculitis: Contribution of Data From the National Network for Vigilance and Prevention of Occupational Pathologies (RNV3P)
|
||
Recruiting |
NCT06277427 -
Refractory ANCA Associated Vasculitis and Lupus Nephritis Treated With BCMA-targeting CAR-T Cells
|
N/A | |
Active, not recruiting |
NCT03967925 -
Rituximab and Belimumab Combination Therapy in PR3 Vasculitis
|
Phase 2 | |
Recruiting |
NCT05630612 -
ETA and AT1 Antagonism in ANCA-vasculitis (SPARVASC)
|
Phase 2 | |
Recruiting |
NCT04316494 -
Hydroxychloroquine in ANCA Vasculitis Evaluation
|
Phase 4 | |
Recruiting |
NCT03698071 -
Soluble CD95 Ligand Role in the Pathophysiology of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis
|
N/A |