Make up for the Epinephrine Autoinjector

Status Completed

Clinical Trial Summary

Part of the problems related with proper use of epinephrine autoinjector may be related with the design of the autoinjector itself.The aim of the study is to investigate whether minor modifications in the design of currently available epinephrine autoinjector ease its use and abrogate common use errors.

Clinical Trial Description

All interns except the ones who previously worked in allergy department in a medical school were invited to the study. Two identical epinephrine autoinjector trainers (Epipen trainer®) were used, one of which was modified by changing gray safety cap to red and placing a yellow arrow pointing to the black injection tip. Written and visual instruction sheet for each trainer was provided. Participants were asked to demonstrate the use of Epipen trainer either with the original or the modified one. They were scored and timed for demonstration. Primary study parameter was the rate of participants correctly demonstrating the use of epinephrine autoinjector. Secondary study parameters were the mean total score, mean time required to administer autoinjector and unintentional self injection of autoinjector into thumb. ;

Study Design

Related Conditions & MeSH terms

Anaphylaxis

Clinical Trial Details

NCT number	NCT01217138
Study type	Interventional
Source	Gazi University
Contact
Status	Completed
Phase	Phase 4
Start date	June 2009
Completion date	May 2010

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT04475003` - Health Literacy Among Caregivers of Children With IgE-mediated Allergy With Risk of Anaphylaxis
Recruiting	`NCT04615065` - Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Not yet recruiting	`NCT06065137` - Standardised Drug Provocation Testing in Perioperative Hypersensitivity	Phase 4
Completed	`NCT00047918` - Blood Factors in Mastocytosis and Unexplained Anaphylaxis and Flushing	N/A
Active, not recruiting	`NCT03953482` - Evaluation of Medical Care and Patient's Knowledge About the Behavior to Take on Secondary Prevention of Anaphylaxis
Recruiting	`NCT05112367` - Epidemiology and Management of Pediatric Anaphylaxis and Allergy in the Pediatric Emergency Department of Montpellier
Completed	`NCT03366298` - Pharmacokinetics of Intramuscular Adrenaline in Food--Allergic Teenagers	Phase 4
Completed	`NCT02958605` - Smartphone Apps for Pediatric Resuscitation	N/A
Completed	`NCT04696822` - Bioavailability of Nasal Epinephrine	Phase 1
Completed	`NCT03942692` - What is the Allergy Follow-up for Children After Anaphylactic Reaction? AFCAR : Allergy Follow-up for Children After Anaphylactic Reaction
Completed	`NCT02854969` - Satisfaction of Patient With Anaphylaxis in the Use of a Medical Device	N/A
Completed	`NCT03282929` - Study to Explore the Pharmacokinetics and Pharmacodynamics of Epinephrine in Healthy Male and Female Subjects With Different Skin to Muscle Depth (STMD)	Phase 1
Recruiting	`NCT01326741` - Clonal Mast Cell Disorders in Exercise-Induced Anaphylaxis	N/A
Completed	`NCT02424136` - PEAnut Anaphylaxis Predictors	N/A
Completed	`NCT01432522` - A Study for Absorption of Intranasal Epinephrine Compared to Conventional Intramuscular Epinephrine	N/A
Completed	`NCT02028065` - A Study to Evaluate the Incidence of Hypersensitivity After Administration of Sugammadex in Healthy Participants (MK-8616-101)	Phase 1
Active, not recruiting	`NCT01247415` - Clinical Investigation on Allergic-like Reactions and Oculo-respiratory Syndrome After the H1N1 Pandemic Vaccine	N/A
Completed	`NCT00868842` - Desensitization of Human Mast Cells: Mechanisms and Potential Utility for Preventing Anaphylaxis	N/A
Completed	`NCT04290507` - Epidemiology and Outcome of Anaphylactic Shocks Admitted to Intensive Care Unit
Recruiting	`NCT05210543` - Acquisition and Long-term Observation of Patients With Severe Allergic Reactions