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Comparation Analgesia Efficiency With Propofol Combine Sevoflurane vs Propofol

Nociceptive Pain Clinical Trial

Official title:
Comparation Analgesia Efficiency With Propofol Combine Sevoflurane vs Propofol Using Index of Nociception (NOX)

Clinical Trial Summary

This study purpose to compare analgesia efficiency of propofol combine with sevoflurane with propofol only using index of Nociception (NOX)

Clinical Trial Description

1. Recently study found sevoflurane plays an important role through spinal nerve peptide receptor (NK.1R), glycine receptor (GlyR), neuron nicotinic receptor (nnAChRs), Methyl-1-methyl-1-day aspartate (NMDA receptor), and TRPV1 receptor (TRPV1 receptor) produce the analgesic efficiency.

2. propofol was traditional sedation reagent.

3. index of Nociception (NOX) was the objective index for analgesia This study purpose to compare analgesia efficiency of Only Propofol and sevoflurane combine with propofol using index of Nociception (NOX) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03841812
Study type Interventional
Source China International Neuroscience Institution
Contact
Status Completed
Phase Phase 3
Start date January 20, 2020
Completion date July 1, 2020
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