Optimal Dosage of Remifentanil for Vertebroplasty

Status Not yet recruiting

Clinical Trial Summary

Percutaneous vertebroplasty has become a mainstay in the management of osteoporotic and malignant vertebral fractures. Procedural analgesia and sedation (PAS) with propofol and remifentanil may provides optimal hypnotic and analgesic effects.

Clinical Trial Description

Percutaneous vertebroplasty has become a mainstay in the management of osteoporotic and malignant vertebral fractures. Many anesthetic methods have been used in percutaneous vertebroplasty; however, there is no gold-standard method. Procedural analgesia and sedation (PAS) are one of the commonly used approaches. For its unique properties, including rapid onset, precise intraoperative control, and a fast recovery profile, remifentanil is preferable to other opioids administration in a target-controlled infusion (TCI) pump. Combination of remifentanil with propofol may improve sedation experience; however, it can increase a risk of respiratory depression. Moreover, propofol and remifentanil are often administered with 2 TCI pumps to, respectively, provide hypnotic and analgesic effects, which together are considered to be an ideal anesthetic technique. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05876039
Study type	Interventional
Source	Tri-Service General Hospital
Contact	Wei-Cheng Tseng, MD
Phone	886-2-2-8792-3311
Email	ndmc_wechern@yahoo.com.tw
Status	Not yet recruiting
Phase	Phase 4
Start date	May 2023
Completion date	April 2025

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