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NCT05851768 Clinical Trial

Efficacy of Dexmedetomidine VS Magnesium Sulphate With Bupivacaine in Erector Spinae Block for Thoracotomy Pain

Analgesia Clinical Trial

Official title:
Analgesic Efficacy of Adding Dexmedetomidine VS Magnesium Sulphate as Adjuvants With Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Post Thoracotomy Pain

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05851768
Other study ID # N-80-2022/NSC
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date May 15, 2023
Est. completion date April 27, 2024

Study information
Verified date February 2024
Source National Cancer Institute, Egypt
Contact Walaa Y Elsabeeny, MD
Phone 01007798466
Email walaa.elsabeeny@nci.cu.edu.eg
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Postoperative pain management is considered an integral part of perioperative care in patients undergoing thoracotomy. In order to reduce these complications, multiple regional techniques have been developed for thoracotomy including Intercostal nerve block, Erectospinae plane block and serratus block. Multiple adjuvants have been used in regional analgesia including adrenaline,clonidine,magnesium sulphate,dexmedatomidine and opoids.

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date April 27, 2024
Est. primary completion date March 25, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: - Age from 18 to 65 years. - Male and female sexes. - ASA I-II.,III - Cancer patients undergoing thoracotomy incisions - Body mass index (BMI) from 18.5 to 30 kg/m2 Exclusion Criteria: - Patient refusal - Known allergy to any of the used drugs - Low platelet count, any coagulation defect

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Bupivacaine
Bupivacaine 0.25%
• Bupivacaine + Magnesium
Bupivacaine 0.25% + Magnesium
• Bupivacaine + Dexmedetomidine
Bupivacaine 0.25% + Dexmedetomidine

Locations
Country Name City State
Egypt Walaa Y Elsabeeny Cairo

Sponsors (1)
Lead Sponsor Collaborator
National Cancer Institute, Egypt

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Total postoperative morphine consumption Total dose of morphine needed postoperatively in the first 24 h First 24 hours postoperatively
Secondary Time to first postoperative rescue analgesia. Time to first postoperative rescue analgesia. First 24 hours postoperatively
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