Comparison of Perioperative Analgesic Efficacy of Femoral Nerve Block, Adductor Canal Block and 4in1 Block

Analgesia Clinical Trial

Official title:

Comparison of Perioperative Analgesic Efficacy in Patients Who Had Femoral Nerve Block, Adductor Canal Block and 4in1 Block Applied in Knee Surgery

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05643040
• Other study ID #: 06/06/2022 139/13
• Status: Recruiting
• Phase: N/A
• Start date: September 1, 2022
• Est. completion date: May 1, 2023

Study information

• Verified date: December 2022
• Source: Diskapi Yildirim Beyazit Education and Research Hospital
• Contact: Funda Atar, MD
• Phone: 5064927432
• Email: fundaatar81[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Central neuraxial and regional anesthesia and analgesia techniques significantly reduce perioperative morbidity and mortality in the knee and below-knee surgeries.Nerve blocks appear to have better analgesic efficacy compared to placebo or patient-controlled analgesia (PCA). In addition, opioid-related side effects such as postoperative nausea, vomiting, pruritus, sedation, and respiratory depression are less. Therefore, interest in regional blocks such as femoral, sciatic, adductor, combined femoral, and sciatic is increasing. The knee joint is innervated by various nerves (genicular nerves) from the femoral, obturator, and sciatic nerves, and a comprehensive but simple technique is needed for postoperative analgesia. Complete and comprehensive postoperative analgesia was possible with this block, a simple single injection technique. The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block, and 4in1 block in patients who will undergo knee surgery.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: May 1, 2023
• Est. primary completion date: February 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 99 Years

Eligibility

Inclusion Criteria:

• Patients between the ages of >18
• undergone knee surgery
• American Society of Anesthesiologists (ASA) classification I-III group.

Exclusion Criteria:

• Patients who do not want to participate in the study coagulopathy peripheral neuropathy local anesthetic drug allergy chronic opioid users anticoagulant users pregnant patients

Related Conditions & MeSH terms

• Analgesia
• Block

Intervention

Other:
• femoral nerve block
To evaluate the intraoperative analgesia effectiveness of femoral block in patients who will have knee surgery.
• adductor canal block
To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery.
• 4in1 block
To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery.

Locations

Country	Name	City	State
Turkey	University of Medical Science, Yildirim Beyazit Training and Research Hospital	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Diskapi Yildirim Beyazit Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

References & Publications (2)

Rodgers A, Walker N, Schug S, McKee A, Kehlet H, van Zundert A, Sage D, Futter M, Saville G, Clark T, MacMahon S. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. BMJ. 2000 Dec 16;321(7275):1493. doi: 10.1136/bmj.321.7275.1493. — View Citation

Roy R, Agarwal G, Pradhan C, Kuanar D. Total postoperative analgesia for total knee arthroplasty: Ultrasound guided single injection modified 4 in 1 block. J Anaesthesiol Clin Pharmacol. 2020 Apr-Jun;36(2):261-264. doi: 10.4103/joacp.JOACP_260_19. Epub 2020 Jun 15. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	intraoperative analgesia efficacy	The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block and 4in1 block in patients who will undergo knee surgery.	perioperative period
Secondary	postoperative analgesia efficacy	The aim of our study is to evaluate the postoperative analgesia efficacy of femoral, adductor canal block and 4in1 block in patients who will undergo knee surgery.	perioperative period