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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT05643040
Other study ID # 06/06/2022 139/13
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date September 1, 2022
Est. completion date May 1, 2023

Study information

Verified date December 2022
Source Diskapi Yildirim Beyazit Education and Research Hospital
Contact Funda Atar, MD
Phone 5064927432
Email fundaatar81@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Central neuraxial and regional anesthesia and analgesia techniques significantly reduce perioperative morbidity and mortality in the knee and below-knee surgeries.Nerve blocks appear to have better analgesic efficacy compared to placebo or patient-controlled analgesia (PCA). In addition, opioid-related side effects such as postoperative nausea, vomiting, pruritus, sedation, and respiratory depression are less. Therefore, interest in regional blocks such as femoral, sciatic, adductor, combined femoral, and sciatic is increasing. The knee joint is innervated by various nerves (genicular nerves) from the femoral, obturator, and sciatic nerves, and a comprehensive but simple technique is needed for postoperative analgesia. Complete and comprehensive postoperative analgesia was possible with this block, a simple single injection technique. The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block, and 4in1 block in patients who will undergo knee surgery.


Recruitment information / eligibility

Status Recruiting
Enrollment 60
Est. completion date May 1, 2023
Est. primary completion date February 1, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years to 99 Years
Eligibility Inclusion Criteria: - Patients between the ages of >18 - undergone knee surgery - American Society of Anesthesiologists (ASA) classification I-III group. Exclusion Criteria: - Patients who do not want to participate in the study coagulopathy peripheral neuropathy local anesthetic drug allergy chronic opioid users anticoagulant users pregnant patients

Study Design


Related Conditions & MeSH terms


Intervention

Other:
femoral nerve block
To evaluate the intraoperative analgesia effectiveness of femoral block in patients who will have knee surgery.
adductor canal block
To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery.
4in1 block
To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery.

Locations

Country Name City State
Turkey University of Medical Science, Yildirim Beyazit Training and Research Hospital Ankara

Sponsors (1)

Lead Sponsor Collaborator
Diskapi Yildirim Beyazit Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

References & Publications (2)

Rodgers A, Walker N, Schug S, McKee A, Kehlet H, van Zundert A, Sage D, Futter M, Saville G, Clark T, MacMahon S. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. BMJ. 2000 Dec 16;321(7275):1493. doi: 10.1136/bmj.321.7275.1493. — View Citation

Roy R, Agarwal G, Pradhan C, Kuanar D. Total postoperative analgesia for total knee arthroplasty: Ultrasound guided single injection modified 4 in 1 block. J Anaesthesiol Clin Pharmacol. 2020 Apr-Jun;36(2):261-264. doi: 10.4103/joacp.JOACP_260_19. Epub 2020 Jun 15. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary intraoperative analgesia efficacy The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block and 4in1 block in patients who will undergo knee surgery. perioperative period
Secondary postoperative analgesia efficacy The aim of our study is to evaluate the postoperative analgesia efficacy of femoral, adductor canal block and 4in1 block in patients who will undergo knee surgery. perioperative period
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