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Clinical Trial Summary

Thoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and in order to reduce the use of the morphinics in the perioperative period. Side effects can be paralytic ileus or nausea and vomiting and delay the enhanced recovery after surgery. Intravenous lidocaine and TEA share several properties like anti hyperalgesia, anti inflammatory effect, intestinal process, anti tumoral effect… which suggests an additive effect of their combination that was not studied yet.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05368753
Study type Interventional
Source Centre Hospitalier Universitaire, Amiens
Contact Ottilie Fumery - Trocheris, MD
Phone 03.22.08.91.08
Email fumery.ottilie@chu-amiens.fr
Status Recruiting
Phase Phase 4
Start date March 9, 2022
Completion date August 2023

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