Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery

Analgesia Clinical Trial

— QLB  

Official title:

Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04670224
• Other study ID #: PI2020_843_0094
• Status: Recruiting
• Phase: N/A
• Start date: March 16, 2021
• Est. completion date: January 2024

Study information

• Verified date: February 2023
• Source: Centre Hospitalier Universitaire, Amiens
• Contact: Ottilie FUMERY- TROCHERIS, MD
• Phone: (33)3 22 08 78 36
• Email: fumery.ottilie[@]chu-amiens.fr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive … Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications delay post-operative recovery. Defined in the 1990s by Professor Henry Kehlet's Danish team, rapid rehabilitation after planned surgery is an approach to overall patient care that aims to rapidly restore previous physical and mental capacities and thus significantly reduce mortality and morbidity. Pain management is at the heart of this program and local anesthesia techniques are at the heart of early rehabilitation programs. Described for just over a decade, Quadratus Lumborum Block (QLB) have shown their effectiveness for analgesia in abdominal, or orthopedic, or obstetrical surgery. Considering the anatomical territory concerned, this locoregional anesthesia technique seems to be very interesting in abdominoplasty to allow early rehabilitation of the patient.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 286
• Est. completion date: January 2024
• Est. primary completion date: December 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult patients admitted for programmed dermo-lipectomy surgery with or without associated liposuction.

Exclusion Criteria:

• Pregnant woman
• Patient under 18 years of age
• Subject under guardianship or curators
• Patient allergic to local anesthetics
• Infection at the puncture sites
• Patient on morphine analgesic over the long term
• Patient on antidepressants for neuropathic pain.

Related Conditions & MeSH terms

• Abdominoplasty
• Analgesia
• Locoregional Anesthesia
• Quadratus Lumborum Block

Intervention

Other:
• QLB anesthesia
The QLB is a bilateral locoregional anesthesia technique, performed after surgery, under general anesthesia and in right and then left lateral decubitus.
• Intravenous anesthesia without QLB
only intravenous anesthesia

Locations

Country	Name	City	State
France	BAR	Amiens

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire, Amiens

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Variation from baseline of morphine consumption		24 hours after surgery
Secondary	Variation from baseline of morphine consumption		1 hour after surgery
Secondary	Variation from baseline of morphine consumption		2 hours after surgery
Secondary	Variation from baseline of morphine consumption		48 hours after surgery