Analgesia Clinical Trial
The investigators aimed to evaluate tramadol-sparing effect of intravenous (IV) ibuprofen in patients undergoing percutaneous nephrolithotomy (PCNL).
Eighty patients who will undergoing PCNL are randomized to intravenous paracetamol (n=40)
and intravenous ibuprofen (n=40) groups. Patients will receive 100 mL of physiologic saline
with 1 g IV paracetamol or 800 mg IV ibuprofen 30 minutes before the end of the operation
and postoperatively 6, 12 and 18 hours after PCNL in the paracetamol and ibuprofen groups,
respectively. Patients in both groups will receive intravenous tramadol with patient
controlled analgesia device (PCA).
The visual analog scale (VAS) will used to evaluate pain intensity scores in the
postoperative period.
Total tramadol consumption, mean VAS score in the 1, 8 and 24 hours, demographic variables,
operative variables, and side effects will record.
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