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Analgesia, Obstetrical clinical trials

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NCT ID: NCT03805607 Active, not recruiting - Postoperative Pain Clinical Trials

IV Ketorolac on Platelet Function Post-Cesarean Delivery

KetoPltAgg
Start date: January 18, 2021
Phase: Phase 4
Study type: Interventional

Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption. The effect of NSAIDs on healthy volunteers results in inhibition of platelet aggregation and prolonged bleeding time. However, in the obstetric population, the presence and degree of platelet inhibition after NSAID exposure is less clear. The investigators plan to use Platelet Aggregometry and Thromboelastography (TEG) to evaluate the effect of ketorolac on platelets.

NCT ID: NCT03167905 Active, not recruiting - Clinical trials for Depression, Postpartum

CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery)

CODEPAD
Start date: June 15, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Postnatal depression affects about 10-15% of women after childbirth. Approximately 3-5% of women experience a moderate-to-severe depression that requires medical attention. This study aims to investigate the implication of pain relief choice in reducing the postnatal depression of women who deliver their babies.