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Anal Fistula clinical trials

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NCT ID: NCT04310800 Recruiting - Anal Fistula Clinical Trials

LIFT-plug vs LIFT, a RCT Trial

LIFT 02
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To validate the effect of Ligation of Intersphincteric Fistula Tract (LIFT) Versus LIFT-plug procedure for Anal Fistula Repair in 7 medical centers

NCT ID: NCT04190862 Recruiting - Anal Fistula Clinical Trials

E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas

Start date: January 22, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if endothelial cells derived from human umbilical vein are safe for use in conjunction with fistulotomy for the treatment of simple anal fistulas. Endothelial cells are a special kind of cell in the body that line the inside surface of blood vessels. The goal of the study is to evaluate the preliminary safety of human umbilical vein cells in anal fistula healing.

NCT ID: NCT04178707 Recruiting - Anal Fistula Clinical Trials

Anal Fistula and Microdialysis - What is Yet to Learn?

Start date: December 10, 2019
Phase: N/A
Study type: Interventional

Anal Fistula can be a challenging condition to treat. Microdialysis has never before been used to examine the inner environment of anal fistula. This is now going to be performed.

NCT ID: NCT04161469 Recruiting - Anal Fistula Clinical Trials

Laser Closure of Anal Fistula (FiLaC)

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Laser closure of the perianal fistula is the minimally invasive and low complication rate procedure which is a life-saving way for complex fistulas, preserving anal sphincter injury. Unfortunately, wide range success rate reported before (30-80%), the investigators are searching to reach better rates. Internal closure of the fistula orifice offered by some authors. The investigators are aimed to identify the efficiency of this.

NCT ID: NCT04155905 Completed - Anal Fistula Clinical Trials

Marsupialization of Anal Fistulotomy Wound Accelerates Healing and Decreases Post Operative Pain

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

comparison between to groups of patients with simple anal fistula one group underwent sistulotomy the other underwent fistulotomy and marsupialization of the wound edges , the investigator tested the incidence of postoperative complications , time of wound healing , operative time

NCT ID: NCT04119700 Recruiting - Anal Fistula Clinical Trials

Fistulectomy and Primary Sphincter rEconstruction vs. endorectaL Advancement Flap in the Treatment of High Anal Fistulas

SELF
Start date: November 4, 2017
Phase: N/A
Study type: Interventional

The optimal method of surgical treatment of complex anorectal fistulas has not been found yet. The aim of this study is to compare two techniques in treatment of high anorectal fistulas. This study purpose to demonstrate that the fistulectomy with dissection from 1/3 to 2/3 of the height of the sphincter complex with primary suturing is technically simpler, equally effective and safe in comparison with muco-muscular endorectal advancement flap.

NCT ID: NCT04073472 Withdrawn - Crohn's Disease Clinical Trials

Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's

IPAAF
Start date: June 1, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and feasibility of using allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat people with an ileal pouch anal anastomosis (IPAA) who develop a fistula in the setting of Crohn's disease of the pouch.

NCT ID: NCT03961984 Completed - Anal Fistula Clinical Trials

Long-term Follow-up of Anal Fistula Plug

Start date: May 2006
Phase:
Study type: Observational

Aim of the study is to evaluate long-term success rate of Biodesign® anal fistula plug for treatment of complex trans-sphincteric anal fistulas.

NCT ID: NCT03937752 Completed - Anal Fistula Clinical Trials

3D Endoanal Ultrasound and Anal Fistula

UFU
Start date: April 1, 2018
Phase:
Study type: Observational

The study aims to evaluate the use of 3D endoanal ultrasound in preoperative management of anal fistula disease.

NCT ID: NCT03878498 Active, not recruiting - Crohn Disease Clinical Trials

Management of Anal Fistula of Crohn Disease

FISTUCROHN
Start date: June 19, 2018
Phase:
Study type: Observational

The management of anal fistula in Crohn Disease is complex. In aim to obtain the healing of the anal fistula, different approaches can be proposed but the best strategy is not yet determined. The aim was to describe the therapeutic management of anal fistula in Crohn Disease.