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REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity Mitigation — REDEL  

Anal Cancer Clinical Trial

Official title:
REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity Mitigation

Clinical Trial Summary

To determine the efficacy of reduced elective nodal radiation in anal cancer patients undergoing chemoradiation in reducing toxicity compared to standard nodal irradiation.

Clinical Trial Description

This is a multi-center, single arm prospective trial to evaluate whether reduced elective nodal dose (30.6 Gy) reduces toxicity as defined by the CTCAE Toxicity Index compared to historic patients treated with standard nodal dose on NRG/RTOG0529 and patient reported GI toxicity using the validated PRO-CTCAE scale for diarrhea compared to historic patients treated on UC-GI-1601. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05902533
Study type Interventional
Source University of Cincinnati
Contact UCCC Clinical Trials Office
Phone 513-584-7698
Email cancer@uchealth.com
Status Recruiting
Phase Phase 2/Phase 3
Start date August 14, 2023
Completion date August 14, 2029
View Details
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