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Triumeq in Amyotrophic Lateral Sclerosis — LIGHTHOUSE II  

Amyotrophic Lateral Sclerosis Clinical Trial

Official title:
Randomised Double-Blind Placebo-Controlled Phase 3 Trial of Triumeq in Amyotrophic Lateral Sclerosis

Clinical Trial Summary

To determine if Triumeq improves survival in Amyotrophic Lateral Sclerosis (ALS) compared with placebo

Clinical Trial Description

This Randomised Double-Blind Placebo Controlled trial seeks to investigate whether the combination medicine Triumeq (dolutegravir 50mg, abacavir 600mg, lamivudine 300mg), already sold in Australia for HIV treatment is effective in delaying progression of theAmyotrophic Lateral Sclerosis (ALS) disease and if it is safe and well tolerated in patients with ALS. This medication is very commonly prescribed for patients with HIV. The secondary aim of this study is to assess patient's health outcomes whilst taking this medication for their ALS. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05193994
Study type Interventional
Source Macquarie University, Australia
Contact Ammar Al-Chalabi, PhD, FRCP
Phone +44 20 7848 5174
Email ammar.al-chalabi@kcl.ac.uk
Status Recruiting
Phase Phase 3
Start date February 24, 2022
Completion date July 1, 2026
View Details
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