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Remote Speech and Swallowing Assessment in ALS

Amyotrophic Lateral Sclerosis Clinical Trial

Official title:
Home Telemonitoring of Bulbar Function by Acoustic Measurement of Swallowing and Speech Sounds in ALS

Clinical Trial Summary

The investigators propose a longitudinal home study of ALS patients to measure the severity of speech and swallowing (bulbar) impairment via a smartphone-based, remote speech and swallow assessment (rSSA). The study is designed to assess the feasibility and validity of such a monitoring intervention. Furthermore, it is proposed that regular monitoring of these two bulbar processes may shed light on their co-evolution over the course of ALS.

Clinical Trial Description

Most individuals with ALS experience bulbar function deterioration over the course of the disease which impacts their quality of life significantly. Furthermore, in some patients, bulbar symptoms are an initial presenting symptom of ALS. Identifying these changes, which may be rapid in some individuals, is complicated by the recent acceleration of virtual care delivery. The investigators propose a longitudinal home study of ALS patients to assess bulbar progression via a smartphone-based, self-administered remote speech and swallow assessment (rSSA). The overall hypothesis is that this monitoring protocol can be used in a way that, 1) is satisfactory to the patient, 2) performs at least as well as standard clinical measures of dysarthria and dysphagia, and 3) resolves the development of emergence of speech and swallowing pathologies in ALS. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04889898
Study type Observational
Source Milton S. Hershey Medical Center
Contact Andrew Geronimo, PhD
Phone 717-531-0003
Email ageronimo@pennstatehealth.psu.edu
Status Recruiting
Phase
Start date January 1, 2022
Completion date September 2024
View Details
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