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New Magnetic Resonance Imaging Biomarkers in Amyotrophic Lateral Sclerosis — IRM-SLA  

Amyotrophic Lateral Sclerosis Clinical Trial

Official title:
New Magnetic Resonance Imaging Biomarkers in Amyotrophic Lateral Sclerosis

Clinical Trial Summary

Amyotrophic lateral sclerosis (ALS) is a disabling and rapidly progressive neurodegenerative disorder. There is no treatment that significantly slows progression. Our project aims to find new biomarkers in MRI at three levels: cerebral, medullary and muscular. These markers could allow an earlier diagnosis of the disease by showing more specific lesions of ALS and to quantify these lesions to measure the progression of the disease. This study will use advanced Magnetic Resonance Imaging (MRI) techniques High field (3T) and very high field (7T) MRI. Results from neurological and electrophysiological tests will be compared to the MRI. Subjects will be recruited from ALS center of Marseille, France. MRI will be done on ALS patients at baseline, at 3 month and at 6 month intervals.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04691011
Study type Interventional
Source Assistance Publique Hopitaux De Marseille
Contact Shahram Attarian
Phone 33491386579
Email shahram.attarian@ap-hm.fr
Status Recruiting
Phase N/A
Start date June 16, 2021
Completion date December 31, 2026
View Details
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