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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04324788
Other study ID # 09.2019.969
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 1, 2020
Est. completion date December 20, 2020

Study information

Verified date September 2021
Source Marmara University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

With the onset of prosthesis use following lower extremity amputations,body shows biomechanical changes according to the amputation level and consequently develops adaptation mechanisms both on the healthy and ampute side. Adaptations in the lumbo-pelvic and lower lumbar regions cause asymmetries in the muscle tissue by causing changes in the morphological structure of the muscle, especially in the muscles of the waist, hip and knee and recruitment. The aim of this study is to investigate the effect of stairing up and down activity on the mechanical properties of lumbal paravertebral muscles in TFA and TTA and its relation with lower lumbar region pain.


Recruitment information / eligibility

Status Completed
Enrollment 28
Est. completion date December 20, 2020
Est. primary completion date April 15, 2020
Accepts healthy volunteers No
Gender Male
Age group 18 Years to 55 Years
Eligibility Inclusion Criteria: - to be TTA and TFA - No complaints of chronic low back pain before amputation - Using prosthesis for at least 6 months - Being able to climb up and down stairs - No history of falls that will cause injury or pain in the past 6 months - Having good prosthesis comfort - BMI<28.5 - Who can have cognitive functions to understand Arabic language Exclusion Criteria: - To be amputated due to congenital and tumor - Who can not have cognitive functions to understand Arabic language - Having orthopedic or neurological disorders that may cause chronic pain or functional impairment in the lumbar region - Ankylosing spondolitis and rheumatoid arthritis patients

Study Design


Intervention

Other:
Group 1
The patients will be asked to go up and down 9-step stair with the highest speed they can make.
Group 2
The patients will be asked to go up and down 9-step stair with the highest speed they can make.

Locations

Country Name City State
Turkey Yasar Tatar Istanbul

Sponsors (1)

Lead Sponsor Collaborator
Marmara University

Country where clinical trial is conducted

Turkey, 

References & Publications (6)

Devan H, Hendrick P, Ribeiro DC, Hale LA, Carman A. Asymmetrical movements of the lumbopelvic region: is this a potential mechanism for low back pain in people with lower limb amputation? Med Hypotheses. 2014 Jan;82(1):77-85. doi: 10.1016/j.mehy.2013.11.012. Epub 2013 Nov 16. — View Citation

Hendershot BD, Bazrgari B, Nussbaum MA. Persons with unilateral lower-limb amputation have altered and asymmetric trunk mechanical and neuromuscular behaviors estimated using multidirectional trunk perturbations. J Biomech. 2013 Jul 26;46(11):1907-12. doi: 10.1016/j.jbiomech.2013.04.018. Epub 2013 May 29. — View Citation

Highsmith MJ, Kahle JT, Kaluf B, Miro RM, Mengelkoch LJ, Klenow TD. PSYCHOMETRIC EVALUATION OF THE HILL ASSESSMENT INDEX (HAI) AND STAIR ASSESSMENT INDEX (SAI) IN HIGH-FUNCTIONING TRANSFEMORAL AMPUTEES. Technol Innov. 2016 Sep;18(2-3):193-201. doi: 10.21300/18.2-3.2016.193. — View Citation

Hu X, Lei D, Li L, Leng Y, Yu Q, Wei X, Lo WLA. Quantifying paraspinal muscle tone and stiffness in young adults with chronic low back pain: a reliability study. Sci Rep. 2018 Sep 25;8(1):14343. doi: 10.1038/s41598-018-32418-x. — View Citation

Kelly-Martin R, Doughty L, Garkavi M, Wasserman JB. Reliability of modified adheremeter and digital pressure algometer in measuring normal abdominal tissue and C-section scars. J Bodyw Mov Ther. 2018 Oct;22(4):972-979. doi: 10.1016/j.jbmt.2018.02.017. Epub 2018 Feb 17. — View Citation

Michaud SB, Gard SA, Childress DS. A preliminary investigation of pelvic obliquity patterns during gait in persons with transtibial and transfemoral amputation. J Rehabil Res Dev. 2000 Jan-Feb;37(1):1-10. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Evaluation of the mechanical properties of the muscle-1 Viscoelastic stiffness [N/m] will be measured in MyotonPro 3 (MYO, Tallin, Estonia Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity
Primary Evaluation of the mechanical properties of the muscle-2 Oscillation frequency (Hz) will be measured in MyotonPro 3 (MYO, Tallin, Estonia Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity
Primary Evaluation of the mechanical properties of the muscle-3 Mechanical stiffness (N/m) will be measured in MyotonPro 3 (MYO, Tallin, Estonia Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity
Primary Evaluation of the back pain Pain will be evaluated by using Visual analog scale ranging 0 (no pain)- 10 (worst pain) Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity
Primary Evaluation of the pressure-pain threshold The pressure-pain threshold (lbs) will be measured in algometer commander (JTECH MEDICAL, MM036_K, 2016) Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity