AML Clinical Trial
— CLAGOfficial title:
A Multicenter Prospective Cohort Study Study of CLAG Regimen in Acute Myeloid Leukemia Patients With First-induction Failure
Most of patients with acute myeloid leukemia achieved complete remission (CR) after primary induction chemotherapy, there were 20-30% patients without CR after first-induction. It was uncertain how to treat these patients. It was investigated in our study that these patients were re-induced with CLAG Regimen. The CR ratio, overall survival (OS) and relapsed-free survival (RFS) was statistically analysed in these patients.
| Status | Not yet recruiting |
| Enrollment | 137 |
| Est. completion date | December 20, 2027 |
| Est. primary completion date | August 20, 2027 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 14 Years to 65 Years |
| Eligibility | Inclusion Criteria: - Acute myeloid leukemia patients with first-induction failure Exclusion Criteria: - Acute myeloid leukemia patients with serious infection and organ dysfunction. |
| Country | Name | City | State |
|---|---|---|---|
| China | Nanfang Hospital of Southern Medical University | Guanzhou | Guangdong |
| China | Nanfang Hospital of Southern Medical University | Guanzhou | Guangdong |
| Lead Sponsor | Collaborator |
|---|---|
| Nanfang Hospital, Southern Medical University |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Study of CLAG Regimen in Acute Myeloid Leukemia Patients With First-induction failure | CLAG Regimen improves CR rate in acute myeloid leukemia patients with first-induction failure | 6 months |
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