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A Phase 2 Study of Gemtuzumab Ozogamicin (GO)-Gilteritinib Combination in Adults With FLT3-ITD Relapse/Refractory (R/R) AML — AGORA-1  

AML Clinical Trial

Official title:
AGORA-1 /ALFA 2100 Study : A Phase 2 Study of Gemtuzumab Ozogamicin (GO)-Gilteritinib Combination in Adults With FLT3-ITD Relapse/Refractory (R/R) AML

Clinical Trial Summary

This is a national, open-label, single-arm, multicenter phase II trial evaluating the safety and efficacy of adding gilteritinib, a new FLT3 inhibitor to the AGORA platform, consisting of the combination of an intermediate dose of cytarabine and a divided dose of GO in adult patients with R / R AML with an FLT3-ITD mutation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05199051
Study type Interventional
Source Centre Antoine Lacassagne
Contact Céline CELLIER-COËLLE
Phone +33 492031778
Email DRCI-Promotion@nice.unicancer.fr
Status Recruiting
Phase Phase 2
Start date June 3, 2023
Completion date March 15, 2027
View Details
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