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Clinical Trial Summary

The purpose of Phase I of this study is to test the safety and tolerability of the investigational drug, OTS167, and that of Phase II of this study is to confirm the potential response benefit of OTS167. OTS167 is a maternal embryonic leucine zipper kinase (MELK) inhibitor which demonstrated antitumor properties in laboratory tests. It is being developed as an anti-cancer drug. In this study OTS167 will be administrated to patients with AML, ALL, advanced MDSs, advanced MPNs, or advanced CML.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02795520
Study type Interventional
Source OncoTherapy Science, Inc.
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date April 2016
Completion date September 2021

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